AI Article Synopsis

  • Post-stroke epilepsy is a frequent complication of acute cerebrovascular disease, significantly impacting patient prognosis and quality of life.
  • This study analyzed EEG characteristics of 10 post-stroke epilepsy patients to enhance the detection of epileptiform discharges when seizures are not occurring.
  • Findings revealed that all patients exhibited epileptiform waves on the side opposite the stroke lesion during interictal periods, indicating a specific EEG pattern associated with post-stroke epilepsy.

Article Abstract

Background: Post-stroke epilepsy is a common and easily overlooked complication of acute cerebrovascular disease. Long-term seizures can seriously affect the prognosis and quality of life of patients. Electroencephalogram (EEG) is the simplest way to diagnose epilepsy, and plays an important role in predicting seizures and guiding medication.

Aim: To explore the EEG characteristics of patients with post-stroke epilepsy and improve the detection rate of inter-seizure epileptiform discharges.

Methods: From January 2017 to June 2020, 10 patients with post-stroke epilepsy in our hospital were included. The clinical, imaging, and EEG characteristics were collected. The stroke location, seizure type, and ictal and interictal EEG manifestations of the patients with post-stroke epilepsy were then retrospectively analyzed.

Results: In all 10 patients, epileptiform waves occurred in the side opposite to the stroke lesion during the interictal stage; these manifested as sharp wave, sharp-wave complex, or spike discharges in the anterior head lead of the side opposite to the lesion.

Conclusion: In EEG, epileptiform waves can occur in the side opposite to the stroke lesion in patients with post-stroke epilepsy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10835697PMC
http://dx.doi.org/10.12998/wjcc.v12.i2.249DOI Listing

Publication Analysis

Top Keywords

post-stroke epilepsy
24
patients post-stroke
20
side opposite
12
eeg characteristics
8
epileptiform waves
8
opposite stroke
8
stroke lesion
8
patients
7
epilepsy
7
post-stroke
6

Similar Publications

Background: Post-stroke epilepsy (PSE) is a major complication of stroke. However, data about the predictors of PSE in patients with acute ischemic stroke (AIS) undergoing mechanical thrombectomy are limited.

Objective: To evaluate the relationship between intraoperative angiographic signs and PSE risk in patients with anterior circulation AIS who underwent mechanical thrombectomy.

View Article and Find Full Text PDF

Gut Microbiome Modulation of Glutamate Dynamics: Implications for Brain Health and Neurotoxicity.

Nutrients

December 2024

Department of Anesthesiology and Critical Care, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 84101, Israel.

The gut-brain axis plays an integral role in maintaining overall health, with growing evidence suggesting its impact on the development of various neuropsychiatric disorders, including depression. This review explores the complex relationship between gut microbiota and glutamate (Glu) regulation, highlighting its effect on brain health, particularly in the context of depression following certain neurological insults. We discuss how microbial populations can either facilitate or limit Glu uptake, influencing its bioavailability and predisposing to neuroinflammation and neurotoxicity.

View Article and Find Full Text PDF

The article presents theses of the resolution of the Interdisciplinary Council of Experts in Psychiatry and Neurology (Moscow, 2024) on the issue of comorbid anxiety disorders (AD) in patients with neurological pathologies. The authors highlight the high prevalence of comorbid ADs and their significant negative impact on the course of underlying diseases, such as epilepsy, pain syndromes and post-stroke conditions. Modern approaches to the diagnosis and treatment of ADs in this group of patients are discussed.

View Article and Find Full Text PDF

Bilingualism is widespread in the world and In Russia and in recent years has been actively considered within the framework of the cognitive reserve concept. The paper provides a review of articles studying cognitive functions in bilingual patients with neurological diseases. Cognitive disorders and dementia in bilinguals occur about 5 years later in comparison with those who speak only one language.

View Article and Find Full Text PDF

Stroke is the leading cause of seizures and epilepsy in adults; however, current guidelines lack robust recommendations for treating post-stroke seizures (PSSs) and epilepsy (PSE). This study aims to demonstrate the long-term safety and efficacy of lacosamide combined with non-vitamin K antagonist oral anticoagulants (NOACs) in patients with PSE and atrial fibrillation (AF). In this prospective longitudinal single-center study, 53 patients with concomitant PSE and AF, admitted between 2022 and 2023, received NOACs for AF management and lacosamide for seizure control.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!