AI Article Synopsis

  • Three new steroid compounds from ashwagandha leaves have been identified, along with thirteen known withanolides, using spectroscopic methods.
  • The research focuses on the chemotypic diversity of ashwagandha found in India, stemming from different plant accessions maintained at the institute.
  • A new alkyl ester glucoside was isolated from the roots and stem of one accession and the leaves of another, adding to the variety of compounds derived from ashwagandha.

Article Abstract

Based on the major components in the leaves, the ashwagandha has been found to exist in several chemotypic forms in India. From the leaves of various accessions of , which were maintained in our institute, three new steroids namely, 4-acetoxy-20β-hydroxy-1-oxo-witha-2,5,24-trienolide (), 24,25-dihydro-14α-hydroxy withanolide D (), 5α,6β,17α,27-tetrahydroxy-1-oxo-witha-2,24-dienolide () together with thirteen known withanolides were identified by spectroscopic methods. From the roots and stem of one accession and leaves of another, a new alkyl ester glucoside () has also been isolated. The new withanolides and have been tentatively named as withanolide 135 A, withanolide 135B and withanolide 108, respectively.

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http://dx.doi.org/10.1080/10286020.2024.2308184DOI Listing

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