AI Article Synopsis
- - Previous studies suggest that oil-based contrast agents during hysterosalpingography (HSG) may boost fertility, but little research focused on women with endometriosis-related infertility.
- - This study evaluated 512 patients undergoing HSG and revealed that those using oil-based contrast had significantly better outcomes, such as higher clinical pregnancy rates (51.39% vs. 27.36%) and live birth rates (31.48% vs. 19.93%).
- - The findings indicate that oil-based contrast mediums are linked to improved fertility outcomes in women with endometriosis-related infertility, compared to non-oil-based mediums.
Article Abstract
Background: Previous studies have suggested that oil-based contrast agents used during hysterosalpingography (HSG) in infertile patients can enhance fertility. However, limited research has investigated the effect of oil-based contrast medium specifically in individuals with endometriosis-related infertility.
Objective: This study aims to explore the impact of oil-based contrast medium on fertility outcomes in women with endometriosis-related infertility.
Methods: Conducted at the First Affiliated Hospital of Guangxi Medical University (January 2020 to June 2022), the study included 512 patients undergoing HSG. Patients were categorized into oil-based and non-oil-based groups, and after propensity score matching, demographic characteristics were compared. Main outcomes included clinical pregnancy rates, live birth rates, early miscarriage rates, and ectopic pregnancy rates.
Results: In our analysis, the Oil-based group showed significantly better outcomes compared to the Non-oil-based group. Specifically, the Oil-based group had higher clinical pregnancy rates (51.39% vs. 27.36%) and increased live birth rates (31.48% vs. 19.93%). This trend held true for expectant treatment, IUI, and IVF/ICSI, except for surgical treatment where no significant difference was observed. After adjusting for various factors using propensity score matching, the Non-oil-based group consistently exhibited lower clinical pregnancy rates compared to the Oil-based group. The Odds Ratio (OR) was 0.38 (95%CI: 0.27-0.55) without adjustment, 0.34 (0.22-0.51) in multivariable analysis, 0.39 (0.27-0.57) using inverse probability of treatment weighting (IPTW), and 0.22 (0.14-0.35) in propensity score matching.
Conclusion: Oil-based contrast medium used in HSG for women with endometriosis-related infertility is associated with higher clinical pregnancy rates and live birth rates compared to Non-oil-based contrast medium.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10837917 | PMC |
| http://dx.doi.org/10.1186/s12958-024-01190-1 | DOI Listing |
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