In this study, we aimed to analyze the literature to date on the utilization of topical calcineurin inhibitors in the management of pruritus among older adults, ages 65 and older. The 16 studies included in the final analysis demonstrated that topical calcineurin inhibitors are well tolerated across ages and are effective in treating a wide variety of chronic pruritic conditions. Collectively, these findings support that topical calcineurin inhibitors should be considered a safe, plausible option for managing age-associated itch. J Drugs Dermatol. 2024;23(2): doi:10.36849/JDD.7190e.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.36849/JDD.7190 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A case of treatment-resistant erosive pustular dermatosis of the scalp.
SAGE Open Med Case Rep
January 2025
Memorial University of Newfoundland, St. John's, NL, Canada.
Erosive pustular dermatosis is a rare and chronic inflammatory condition of the scalp which can be mistaken for cutaneous malignancy, precancerous lesions, dermatitis or pyoderma gangrenosum. The recurrent and resistant characteristics of erosive pustular dermatosis of the scalp pose a challenge to successful management and remission of the condition. The purpose of this case report is to provide management options and treatment recommendations for refractory cases of erosive pustular dermatosis of the scalp.
View Article and Find Full Text PDFEfficacy of dupilumab with concomitant topical calcineurin inhibitors treatment for preschool children with atopic dermatitis: a retrospective cohort study.
Ann Med
December 2025
Department of Dermatology, Affiliated Hangzhou First People's Hospital, Westlake University School of Medicine, Hangzhou, China.
Background/objective: Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease that typically occurs in childhood/infancy and is associated with complications like extracutaneous atopic morbidity. Providing systemic treatment for pediatric AD patients with unmet comprehensive medical needs remains challenging. We present a cohort study describing the efficacy and safety of dupilumab combined with topical calcineurin inhibitors (TCI) in children with moderate-to-severe atopic dermatitis under the age of 6 years.
View Article and Find Full Text PDFTopical Tacrolimus in Vitiligo: Consensus Paper from the Pigmentary Disorders Society.
Clin Cosmet Investig Dermatol
December 2024
Consultant Dermatologist, Indore, Madhya Pradesh, India.
Background: Tacrolimus, a topical calcineurin inhibitor (TCI) with immunomodulatory effects, is considered a viable treatment option for vitiligo. A consensus building exercise was undertaken to determine the role and clinical utility of topical tacrolimus in the management of vitiligo using input from experts in the field of dermatology.
Methods: Seventeen experts collaborated to create consensus statements using a modified Delphi methodology.
[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023].
Dermatologie (Heidelb)
December 2024
Klinik und Poliklinik für Dermatologie und Allergologie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
Article Synopsis
- Granuloma annulare (GA) is a non-infectious skin condition that can become widespread in some patients; this study focused on those with disseminated GA in a German hospital.
- A total of 239 patients were studied, with 33 having confirmed disseminated GA, predominantly affecting women around the age of 57, and many reporting little to no symptoms.
- Treatment options included glucocorticoids and phototherapy, but only a small percentage achieved remission, highlighting the need for more effective clinical trials for new therapies.
Nail Lichen Striatus and Its Differential Diagnoses.
Skin Appendage Disord
December 2024
Private Dermatology Clinic, Antalya, Turkey.
Background: Lichen striatus (LS) is a benign, mostly self-limiting dermatological condition, primarily affecting the skin, and sometimes the nails. It is characterised by the sudden onset of a band-like rash, typically following Blaschko lines. The exact cause of LS is not well established, but it is believed to be an abnormal immune response to the altered keratinocyte clone after a triggering event.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!