Objective: Colorectal cancer (CRC) has become the third most commonly diagnosed type of cancer in the world. Based on the risk factors for colorectal cancer (behavior, lifestyle), it is important to better understand the behavioral and psychological characteristics of the individual associated with timely seeking medical help, coping with the extreme situation of diagnosis, and the course of the disease. This determined the purpose of the study: identify the psychological characteristics of patients with colorectal cancer associated with the stage of diagnosis verification and the prognosis of disease outcome.
Patients And Methods: Coping, quality of life, and resilience, as well as clinical and sociodemographic variables were studied in 72 patients diagnosed with colorectal cancer. The design of the study involved studying the relationship between the stage of cancer and the prognosis of the outcome of the disease, as well as the role of psychological variables in the timeliness of diagnosis and predicting the outcome of cancer.
Results: The stage of verification of colorectal cancer is associated with the prognosis of the outcome of the cancer; the later colorectal cancer is verified, the more unfavorable the prognosis of the outcome of the oncological disease. Escape-avoidance coping is associated with the verification stage of colorectal cancer; pronounced avoidance is associated with the late verification stage. Coping strategies such as seeking social support, positive reappraisal, risk-taking, pain intensity, and role functioning significantly influence the prognosis of colorectal cancer outcomes.
Conclusions: The psychological characteristics of the personality of patients with colorectal cancer have been identified, which, by determining the behavior of patients, affect the timeliness of diagnosis verification and the prognosis of the outcome of the disease.
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http://dx.doi.org/10.26355/eurrev_202401_35080 | DOI Listing |
Cancer Commun (Lond)
January 2025
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Mol Med Rep
March 2025
Key Laboratory of Immune Microenvironment and Inflammatory Disease Research in Universities of Shandong Province, School of Basic Medical Sciences, Shandong Second Medical University, Weifang, Shandong 261053, P.R. China.
Colorectal cancer (CRC) is one of the most common cancers worldwide. With the growing understanding of immune regulation in tumors, the complement system has been recognized as a key regulator of tumor immunity. Traditionally, the complement cascade, considered an evolutionarily conserved defense mechanism against invading pathogens, has been viewed as a crucial inhibitor of tumor progression.
View Article and Find Full Text PDFCurr Med Chem
January 2025
Department of Infectious Diseases, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, Luoyang, 471000, Henan, China.
Gastrointestinal tumors, including colorectal and liver cancer, are among the most prevalent and lethal solid tumors. These malignancies are characterized by worsening prognoses and increasing incidence rates. Traditional therapeutic approaches often prove ineffective.
View Article and Find Full Text PDFFront Oncol
December 2024
Department of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan, China.
Introduction: Despite the established influence of gut bacteria, the role of the gut virome in modulating colorectal cancer (CRC) patient chemotherapy response remains poorly understood. In this study, we investigated the impact of antiviral (AV) drug-induced gut virome dysbiosis on the efficacy of 5-FU in CRC treatment.
Methods: Using a subcutaneous CRC mouse model, we assessed tumor growth and immune responses following AV treatment, fecal microbiota transplantation (FMT), and 5-FU administration.
Cureus
December 2024
Biostatistics and Epidemiology, Rutgers University, Piscataway, USA.
Background Various studies have evaluated the quality of health-related information on TikTok (ByteDance Ltd., Beijing, China), including topics such as COVID-19, diabetes, varicoceles, bladder cancer, colorectal cancer, and others. However, there is a paucity of data on studies that examined TikTok as a source of quality health information on human papillomavirus (HPV).
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