Physical exercise interventions to prevent falls for older adults at risk of falling are widespread in many countries; however, there is insufficient knowledge of the impact of long-term exercise on the fall discriminating ability of existing fall-prediction indicators. This study measured physical and cognitive indicators of the fall risk, including the timed up and go (TUG), walking speed (WS), and plantar tactile threshold (PTT), in 124 community-dwelling older adults with care needs who were continuing an exercise program. Logistic regression analyses were used to determine factors associated with falls in the 87 participants who could adhere to the exercise continuously for 12 months. The PTT was significantly higher in fallers, while the TUG and WS did not differ significantly between fallers and non-fallers. The only index significantly associated with falls was the PTT ( = 1.20). The fall identification ability was better for PTT (AUC = 0.63), whereas TUG (AUC = 0.57) and WS (AUC = 0.52) were lower than previously reported scores. In conclusion, long-term exercise was found to improve scores on the fallprediction indicators by physical performance, but to decrease their ability to identify future falls. PTT may complement the ability to identify falls in such elderly populations.
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http://dx.doi.org/10.1177/23337214241229328 | DOI Listing |
Addiction
January 2025
Department of Addictions, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Background And Aims: Many vaping products feature bright colors and novel brand names and flavor descriptors, which may appeal to youth. We measured the strength of the associations between e-liquid packaging design (branded, white standardized or white standardized limiting brand and flavor descriptors) and perceived peer interest in trying the e-liquids among youth.
Design: A between-subjects online experiment.
J Child Lang
January 2025
Center for Data Science in Humanities, Institute of Humanities, Chosun University, Gwangju, Korea.
We investigated the dynamics of communicative initiation in infant-caregiver interactions across ages and language abilities. Analyses of 228 Language ENvironment Analysis (LENA) recordings from 141 Korean adult-child dyads (60 girls; aged 7-30 months) replicated the initiator effect reported in North American populations. This effect, demonstrated by longer utterances, more frequent speech, and shorter response times in self-initiated interactions for both children and adults, suggests potential cross-cultural consistency in this conversational dynamic and remained consistent across ages in most conversational measures.
View Article and Find Full Text PDFAm J Cancer Res
December 2024
Department of Hematology, Cancer Hospital Affiliated to Shanxi Medical University/Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences Taiyuan 030013, Shanxi, China.
Objective: To analyze the clinical characteristics and molecular biomarkers of adult T-cell lymphoblastic lymphoma (T-LBL) to identify prognostic factors, and to evaluate the efficacy of different chemotherapy regimens, providing a basis for optimizing treatment strategies for T-LBL.
Methods: A total of 89 Patients aged 18-72 years with T-LBL, confirmed via histopathological examination of lymph nodes, extranodal tissues, or bone marrow, were retrospectively included. Clinical data, treatment details, and mutational profiles were collected.
Am J Cancer Res
December 2024
Department of Otorhinolaryngology, Lo-Hsu Medical Foundation, Lotung Poh-Ai Hospital Yilan 265, Taiwan.
Betel nut chewing, common in several Asian populations, is linked to increased cancer risk, including oral, esophageal, gastric, and hepatocellular carcinoma. Aspirin shows potential as a chemopreventive agent. This study investigates the association between aspirin use and cancer risk among betel nut chewers.
View Article and Find Full Text PDFHeart Rhythm O2
December 2024
Pfizer Inc, New York, New York.
Background: Prediction models for atrial fibrillation (AF) may enable earlier detection and guideline-directed treatment decisions. However, model bias may lead to inaccurate predictions and unintended consequences.
Objective: The purpose of this study was to validate, assess bias, and improve generalizability of "UNAFIED-10," a 2-year, 10-variable predictive model of undiagnosed AF in a national data set (originally developed using the Indiana Network for Patient Care regional data).
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