AI Article Synopsis

  • - The study presents a case where molecular-targeted agents, like sorafenib, successfully treated a patient with unresectable hepatocellular carcinoma (HCC), leading to a significant reduction in tumor size and disappearance of lung metastases.
  • - A 61-year-old male diagnosed with unresectable HCC underwent sorafenib treatment, which improved his condition, allowing for subsequent treatments like radiofrequency ablation (RFA) and transarterial chemoembolization (TACE).
  • - After eight years, the patient remains alive and free from recurrence, indicating potential long-term survival through a combination of targeted therapy and multimodal treatments.

Article Abstract

In this study, we report a case in which molecular-targeted agents have been shown to be effective in the treatment of unresectable hepatocellular carcinoma(HCC), which has enabled a radical treatment, conversion therapy, and long-term survival with multimodality treatment including RFA. Case: A 61-year-old male, abdominal ultrasonography revealed a large liver tumor and multiple lesions mainly in the right lobe of the liver. He was diagnosed as having unresectable HCC, and treatment with sorafenib was initiated. After treatment, the tumor was clearly reduced in size and the lung metastases disappeared. Five years later, recurrence was observed at the treated site of S7/8, and RFA was performed again after TACE. The patient has survived for 8 years without recurrence.

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