Management of joint infection is an evolving topic. This article reviews the literature on the management of native and prosthetic joint infection and suggests some areas of improvement in short- and long-term management which could lead to better patient outcomes. Surgical management is the mainstay of treatment for native or prosthetic knee infection and aspiration should only be used for diagnostic purposes. A multidisciplinary team approach and compliance with national guidelines, alongside referral networks and pooling of expertise, should be mandatory to improve patient outcomes.
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http://dx.doi.org/10.12968/hmed.2023.0219 | DOI Listing |
Trop Med Health
January 2025
Department of Paediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan.
Background: Vietnam experienced the first COVID-19 domestic outbreak due to the Wuhan strain (B.1.1) in Da Nang from July 2020.
View Article and Find Full Text PDFKnee Surg Relat Res
January 2025
Department of Orthopedics, Seoul National University College of Medicine, Seoul, South Korea.
Introduction: Prosthetic joint infection (PJI) is one of the most common and detrimental complications of total knee replacement arthroplasty (TKA). Despite extensive efforts, including two-stage reimplantation, to eradicate PJI, it still recurs in a substantial number of patients. However, the risk factors of recurrence after two-stage reimplantation of the knee have not been established.
View Article and Find Full Text PDFBiol Res
January 2025
School of Pharmacy, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Background: Protein palmitoylation, a critical posttranslational modification, plays an indispensable role in various cellular processes, including the regulation of protein stability, mediation of membrane fusion, facilitation of intracellular protein trafficking, and participation in cellular signaling pathways. It is also implicated in the pathogenesis of diseases, such as cancer, neurological disorders, inflammation, metabolic disorders, infections, and neurodegenerative diseases. However, its regulatory effects on sperm physiology, particularly motility, remain unclear.
View Article and Find Full Text PDFOrthopadie (Heidelb)
January 2025
Sporthopaedicum Straubing und Regensburg, Regensburg, Deutschland.
Pre- and perioperative management of malnutrition is crucial for the success of hip and knee arthroplasties. Various studies indicate that malnutrition, particularly when associated with vitamin D deficiency, significantly increases the risk of postoperative complications such as periprosthetic fractures and infections, prolonged hospital stays, and higher mortality rates. Adequate preoperative nutritional intake, including vitamin D supplementation, can improve arthroplasty outcomes.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Infection Services, University Hospitals Birmingham NHS Foundation Trust, Birmingham, Birmingham, UK.
is a ubiquitous environmental fungus, and several osteomyelitis cases have been reported in recent years. We present the case of a woman in her 70s who sustained a comminuted open ankle fracture, with garden soil contamination of the wound, which was treated according to orthoplastic principles. The patient developed osteomyelitis 6 months postsurgery.
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