AI Article Synopsis
- - Oral squamous cell carcinoma is the 17th most common cancer globally, primarily linked to risk factors like alcohol and tobacco use, alongside diet and genetic influences.
- - Diagnosis typically relies on biopsy but often occurs late, leading to a poor outlook; advancements like Artificial Intelligence and salivary biomarker evaluation might help with earlier detection.
- - Current treatment mainly involves surgery, which can be drastic, though future options may include immunotherapies and utilizing the immune microenvironment for new prognostic markers.
Article Abstract
Oral Squamous cell carcinoma represent the 17 most frequent cancer in the world. The main risk factors are alcohol and tobacco consumption but dietary, familial, genetic, or oral diseases may be involved in oral carcinogenesis. Diagnosis is made on biopsy, but detection remains late, leading to a poor prognosis. New technologies could reduce these delays, notably Artificial Intelligence and the quantitative evaluation of salivary biological markers. Currently, management of oral cancer consists in surgery, which can be mutilating despite possible reconstructions. In the future, immunotherapies could become a therapeutic alternative and the immune microenvironment could constitute a source of prognostic markers.
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| http://dx.doi.org/10.1051/medsci/2023196 | DOI Listing |
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