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http://dx.doi.org/10.1002/pbc.30907 | DOI Listing |
J Pediatr Surg
September 2024
Department of Pediatric Surgery, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China. Electronic address:
Background: This study generalized and analyzed the clinical attributes observed in patients afflicted with Kaposiform hemangioendothelioma (KHE) with the aim of elucidating the risk factors contributing to the manifestation of Kasabach-Merritt phenomenon (KMP).
Methods: We retrospectively analyzed 96 pediatric cases diagnosed with KHE at the Children's Hospital of Fudan University from January 2013 to December 2021. Among them, 62 patients (65%) showed KMP (KHE + KMP group), while 34 patients (35%) did not (KHE-KMP group).
Indian J Hematol Blood Transfus
July 2024
Department of Pediatrics, Army Hospital Research and Referral, Delhi, 110010 India.
Vascular tumours (VT) with Kasabach-Merritt phenomenon (KMP) are rare and aggressive tumors. In absence of evidence based treatment guidelines, we studied varied presentation and response to therapy with vincristine and steroids in VT with KMP at our center. In this retrospective observational study, infants with a symptomatic/disfiguring rapidly growing VT with features of KMP were included.
View Article and Find Full Text PDFPediatr Blood Cancer
April 2024
Department of Pediatrics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Eur Rev Med Pharmacol Sci
July 2023
Department of Orthopedics and Traumatology, Honghui Hospital, Xi'an JiaoTong University, Xi'an, China.
Background: Kaposiform hemangioendothelioma (KHE) is a borderline vascular tumor between hemangioma and malignant angiosarcoma. While KHE has strong local invasion with rare spontaneous regression, it is not observed with distant metastasis. Even if KHE is asymptomatic or without the Kasabach-Merritt phenomenon (KMP), bone or joint invasion should clearly receive proactive treatment.
View Article and Find Full Text PDFPrecis Clin Med
June 2023
Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
Introduction: The Kasabach-Merritt phenomenon (KMP) is a severe complication of kaposiform hemangioendothelioma (KHE). The risk factors for KMP need further investigation.
Methods: The medical records of patients with KHE were reviewed.
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