A 45-year-old woman was hospitalized with severe coronavirus disease 2019 pneumonia. Following cytokine storm-induced multiorgan failure and lethal arrhythmia, the patient developed a sustained coma with flaccid quadriplegia. A cerebrospinal fluid examination excluded infectious and immunogenic encephalopathies, and diffusion-weighted magnetic resonance imaging demonstrated high-intensity areas in the white matter with a cortex-sparing distribution, suggesting delayed post-hypoxic leukoencephalopathy. As a result of intensive cardiopulmonary support for a month, the neurological function gradually recovered. Based on the reversible clinical course noted in this patient, accurate diagnosis and persistent medical approaches are important for the management of coronavirus disease 2019-related delayed post-hypoxic leukoencephalopathy.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11081903 | PMC |
http://dx.doi.org/10.2169/internalmedicine.1412-22 | DOI Listing |
Intern Med
November 2024
Department of Radiology, Jichi Medical University, Japan.
World J Clin Cases
October 2024
Department of Neurology, University of Massachusetts Chan Medical School, Worcester, MA 01655, United States.
Heliyon
September 2024
Department of Neurology, China-Japan Union Hospital of Jilin University, Changchun, China.
Tomography
June 2024
Mātai Medical Research Institute, Tairāwhiti Gisborne 4010, New Zealand.
Pediatr Res
June 2024
Department of Pediatric Research, Oslo University Hospital, Oslo, Norway.
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