AI Article Synopsis

  • * Tests ruled out infections or immune issues, and brain imaging indicated delayed post-hypoxic leukoencephalopathy, a condition caused by lack of oxygen.
  • * After a month of intensive treatment, the patient's neurological function improved, highlighting the need for accurate diagnosis and ongoing care in managing COVID-19-related brain issues.

Article Abstract

A 45-year-old woman was hospitalized with severe coronavirus disease 2019 pneumonia. Following cytokine storm-induced multiorgan failure and lethal arrhythmia, the patient developed a sustained coma with flaccid quadriplegia. A cerebrospinal fluid examination excluded infectious and immunogenic encephalopathies, and diffusion-weighted magnetic resonance imaging demonstrated high-intensity areas in the white matter with a cortex-sparing distribution, suggesting delayed post-hypoxic leukoencephalopathy. As a result of intensive cardiopulmonary support for a month, the neurological function gradually recovered. Based on the reversible clinical course noted in this patient, accurate diagnosis and persistent medical approaches are important for the management of coronavirus disease 2019-related delayed post-hypoxic leukoencephalopathy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11081903PMC
http://dx.doi.org/10.2169/internalmedicine.1412-22DOI Listing

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