Psychophysiological research is an inherently complex undertaking due to the nature of the data, and its analysis is characterized by many decision points that shape the final dataset and a study's findings. These decisions create a "multiverse" of possible outcomes, and each decision from study conceptualization to statistical analysis can lead to different results and interpretations. This review describes the concept of multiverse analyses, a methodological approach designed to understand the impact of different decisions on the robustness of a study's findings and interpretation. The emphasis is on transparently showcasing different reasonable approaches for constructing a final dataset and on highlighting the influence of various decision points, from experimental design to data processing and outcome selection. For example, the choice of an experimental task can significantly impact event-related brain potential (ERP) scores or skin conductance responses (SCRs), and different tasks might elicit unique variances in each measure. This review underscores the importance of transparently embracing the flexibility inherent in psychophysiological research and the potential consequences of not understanding the fragility or robustness of experimental findings. By navigating the intricate terrain of the psychophysiological multiverse, this review serves as an introduction, helping researchers to make informed decisions, improve the collective understanding of psychophysiological findings, and push the boundaries of the field.
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http://dx.doi.org/10.1016/j.ijpsycho.2024.112311 | DOI Listing |
Elife
January 2025
Department of Neurology, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.
Chronic pain is a prevalent and debilitating condition whose neural mechanisms are incompletely understood. An imbalance of cerebral excitation and inhibition (E/I), particularly in the medial prefrontal cortex (mPFC), is believed to represent a crucial mechanism in the development and maintenance of chronic pain. Thus, identifying a non-invasive, scalable marker of E/I could provide valuable insights into the neural mechanisms of chronic pain and aid in developing clinically useful biomarkers.
View Article and Find Full Text PDFQual Life Res
December 2024
Center for Patient-Centered Outcomes Research, Medizinische Klinik mit Schwerpunkt für Psychosomatik, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Charitéplatz 1, 10097, Berlin, Germany.
Pers Soc Psychol Bull
December 2024
Radboud University, Nijmegen, The Netherlands.
The second coming of the Ku Klux Klan popularized the Klan and its ideas in the early 1920s, terrorizing Black American, their allies, and others deemed un-American. This article investigates the extent to which the cultural legacy of racial hatred of the Klan has persisted over the years. We use data from large online databases, multiverse analyses, and spatial models to evaluate whether regions with more historical Klan activity show higher levels of modern-day racial bias, and more modern-day White Supremacist activity.
View Article and Find Full Text PDFJ Affect Disord
January 2025
Department of Clinical, Neuro-, and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Background: The varying sizes of effects in published meta-analyses on digital interventions for depression prompt questions about their efficacy.
Methods: A systematic search in Embase, PsycINFO, and PubMed identified 125 randomised controlled trials up to February 2023, comparing digital interventions for depression against inactive controls. The stability of results was evaluated with a multiverse meta-analysis, thousands of meta-analyses were conducted based on different combinations of analytical choices, like target populations, intervention characteristics, and study designs.
J Exp Psychol Learn Mem Cogn
October 2024
Department of Experimental Psychology, University College London.
Cronbach (1957) famously noted the divergence between the experimental and psychometric traditions in psychology and called for a unification, but many domains of cognitive experimental psychology continue to pay minimal heed to basic psychometric principles. The present article considers the lack of attention devoted to the reliability of measures extracted in a popular visual search task for studying putatively unconscious mental processes, , and the inferential fallacies that this neglect can cause. Two experiments (total = 200) demonstrated that the reliability of contextual cuing and awareness measures can be increased by three manipulations designed to increase between-participant variability in search performance.
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