AI Article Synopsis
- - High altitude retinopathy (HAR) is a common eye issue that typically occurs when people ascend to high altitudes, with symptoms like retinal vascular dilatation, edema, and occasional hemorrhage; vision is usually not severely affected.
- - Current research focuses on factors like blood flow changes, damage to the blood-retinal barrier, oxidative stress, and inflammation, indicating that HAR is related to hypoxia, especially when altitude increases.
- - The correlation of HAR with altitude-related illnesses such as acute mountain sickness (AMS) and high-altitude cerebral edema (HACE) highlights the importance of understanding HAR, as proper ascent strategies and medical insights from both traditional Chinese medicine and Western medicine can help in prevention and treatment. *
Article Abstract
High altitude retinopathy (HAR) is a common ocular disorder that occurs on ascent to high altitude. There are many clinical symptoms, retinal vascular dilatation, retinal edema and hemorrhage are common. These usually do not or slightly affect vision; rarely, severe cases develop serious or permanent vision loss. At present, the research progress of HAR mainly focuses on hemodynamic changes, blood-retinal barrier damage, oxidative stress and inflammatory response. Although the related studies on HAR are limited, it shows that HAR still belongs to hypoxia, and hypobaric hypoxia plays an aggravating role in promoting the development of the disease. Various studies have demonstrated the correlation of HAR with acute mountain sickness (AMS) and high-altitude cerebral edema (HACE), so a deeper understanding of HAR is important. The slow ascent rates and ascent altitude are the key to preventing any altitude sickness. Research on traditional chinese medicine (TCM) and western medicine has been gradually carried out. Further exploration of the pathogenesis and prevention strategies of HAR will provide better guidance for doctors and high-altitude travelers.
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| http://dx.doi.org/10.1016/j.tmaid.2024.102689 | DOI Listing |
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