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Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop. | LitMetric

AI Article Synopsis

  • - The NIAID organized a workshop focusing on the use of various omics approaches (like genomics, transcriptomics, and microbiomics) to study asthma and allergic diseases, bringing together experts from different fields.
  • - Participants discussed the current trends, challenges, and emerging strategies in asthma and allergy research, emphasizing the need for integrated and rigorous analytic frameworks.
  • - The workshop highlighted the importance of cross-disciplinary collaboration to enhance understanding and improve care for asthma and allergic conditions.

Article Abstract

Studies of asthma and allergy are generating increasing volumes of omics data for analysis and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) assembled a workshop comprising investigators studying asthma and allergic diseases using omics approaches, omics investigators from outside the field, and NIAID medical and scientific officers to discuss the following areas in asthma and allergy research: genomics, epigenomics, transcriptomics, microbiomics, metabolomics, proteomics, lipidomics, integrative omics, systems biology, and causal inference. Current states of the art, present challenges, novel and emerging strategies, and priorities for progress were presented and discussed for each area. This workshop report summarizes the major points and conclusions from this NIAID workshop. As a group, the investigators underscored the imperatives for rigorous analytic frameworks, integration of different omics data types, cross-disciplinary interaction, strategies for overcoming current limitations, and the overarching goal to improve scientific understanding and care of asthma and allergic diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999353PMC
http://dx.doi.org/10.1016/j.jaci.2024.01.014DOI Listing

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