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[Organ conservation and transportation modalities]. | LitMetric

[Organ conservation and transportation modalities].

Rev Prat

Unité Ischémie reperfusion, métabolisme et inflammation stérile en transplantation (IRMETIST), UMR U1313, CHRU de Poitiers, Poitiers, France. Service de biochimie, pôle Biospharm, CHRU de Poitiers, Poitiers, France. Université de Poitiers, faculté de médecine et de pharmacie, Poitiers, France.

Published: November 2023

ORGAN CONSERVATION AND TRANSPORTATION MODALITIES. Organ preservation in transplantation is an essential step in the graft journey between the donor and the recipient. The modalities of preservation have become a major element in this process given the evolution of donors in terms of age and associated comorbidities. This situation has led to the evolution of preservation in terms of the composition of solutions and perfusion technologies for all organs. Several concepts have thus emerged with extracellular type composition and the contribution of new molecules such as high molecular weight polyethylene glycols. The evolution also concerns new techniques such as normothermic abdominal circulation and perfusion machines with the use of hypothermia or normothermia and the oxygenation of the medium. Finally, new molecules are available to the teams and other concepts such as perfusion, evaluation and rehabilitation units.

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