The efficacy of pelvic radiation in the management of locally advanced stage rectal cancer has come under scrutiny in the context of modern precision medicine and systemic therapy as evidenced by recent clinical trials such as FOWARC ( 2019; 37: 3223-3233), NCT04165772 ( 2022; 386: 2363-2376), and PROSPECT ( 2023; 389: 322-334). In this review, we comprehensively assess these pivotal trials and offer additional insights into the evolving role of pelvic radiation in contemporary oncology.
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| http://dx.doi.org/10.5306/wjco.v15.i1.1 | DOI Listing |
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