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Article Synopsis
  • The study aimed to examine how the full-field stimulus test (FST) relates to patients' self-reported visual function in those with retinitis pigmentosa (RP) by utilizing the Michigan Retinal Degeneration Questionnaire (MRDQ).
  • 31 RP patients participated, measuring their retinal sensitivity using FST while completing the MRDQ to derive disability scores across various visual function areas; significant correlations were found between FST results and specific MRDQ domains.
  • Results indicated strong links between FST measures, particularly with blue stimuli, and self-reported functional impairments, suggesting FST could serve as a valuable endpoint in RP clinical trials.
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Introduction: Nephronophthisis 12 is a rare condition and only two cases have been reported to associate with retinopathy. Herein we present the third case in scientific literature, and the first with vision-quality exams.

Clinical Case: The case was a 28-year-old male with the mutations c.

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Retinal morphology, specifically in its curvature, and ocular aberrations change when the eye adapts to different lighting conditions, including photopic, scotopic, mesopic, blue light, and red light. Sixty healthy young subjects with refractive error less than ±4.00 D of sphere and 3.

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Background: We aimed to study the optical and retinal modifications that occur after adapting to different lighting conditions including photopic, mesopic, scotopic, blue light and red light conditions.

Methods: Thirty young healthy subjects with a mean age of 23.57 ± 3.

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UNVEILING THE HIDDEN: EARLY MANIFESTATIONS OF EXTENSIVE MACULAR ATROPHY WITH PSEUDODRUSEN-LIKE APPEARANCE.

Retin Cases Brief Rep

January 2025

Eye Clinic, Luigi Sacco Hospital, Department of Biomedical and Clinical Science, University of Milan, Milan, Italy.

Purpose: To describe novel microperimetry and imaging findings in two patients affected by extensive macular atrophy with pseudodrusen-like appearance without signs of retinal pigment epithelium atrophy.

Methods: Case series. Both patients underwent mesopic and dark-adapted two-color scotopic microperimetry, followed by multimodal imaging assessment including ultra-widefield photography, fundus autofluorescence, high-resolution optical coherence tomography, optical coherence tomography angiography, and high-magnification module.

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