AI Article Synopsis
- Cancer is a major health issue, causing high rates of illness and death, indicating a need for new approaches in drug development.
- Pigs have biological similarities to humans, making them a promising alternative for research in cancer treatments.
- The creation of a transgenic "Oncopig" line allows researchers to study organ-specific tumors, which could lead to innovative therapeutic strategies.
Article Abstract
Cancer remains a leading cause of morbidity and mortality, and a paradigm shift is needed to fundamentally revisit drug development efforts. Pigs share close similarities to humans and may serve as an alternative model. Recently, a transgenic 'Oncopig' line has been generated to induce solid tumors with organ specificity, opening the potential of Oncopigs as a platform for developing novel therapeutic regimens.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939816 | PMC |
| http://dx.doi.org/10.1016/j.trecan.2024.01.005 | DOI Listing |
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