AI Article Synopsis
- The study investigates the relationship between total small vessel disease (SVD) scores from MRI and carotid ultrasonography findings as indicators of stroke risk in patients with small-vessel occlusion.
- Researchers analyzed 122 stroke patients, categorizing them into low-score (SVD score of 2 or less) and high-score (SVD score of 3 or more) groups using atherosclerotic factors.
- Results showed that patients with higher SVD scores had significantly elevated Gosling pulsatility index (PI) values in the internal carotid artery, suggesting that ICA-PI could serve as an alternative predictor for SVD scores, potentially aiding in stroke prevention interventions.
Article Abstract
Background And Purpose: The total small vessel disease (SVD) score, calculated using magnetic resonance imaging (MRI), is used to assess the risk of cerebral infarction. Stroke patients with total SVD scores of three or higher are reported to have a significantly increased risk of recurrent stroke. Similar to the total SVD score, carotid ultrasonography findings have been reported to be indicators of atherosclerosis. Although the total SVD score effectively reflects SVD progression, its correlation with carotid ultrasonography findings remains unknown. We aimed to investigate whether there is a relationship between these two factors.
Methods: Patients with small-vessel occlusion within 24 h of onset were retrospectively selected. Atherosclerotic factors were evaluated using the left-right average Gosling pulsatility index (PI) in the internal carotid artery (ICA-PI) and cardio-ankle vascular index (CAVI). Differences in clinical backgrounds, including atherosclerotic factors, were evaluated by dividing patients into two groups: those with a total SVD score of two or less (low-score group) and those with scores of three or more (high-score group).
Results: A total of 122 patients were included in this study. ICA-PI was significantly higher in the high-score group than in the low-score group. A high score was independently correlated with ICA-PI after adjusting for age, CAVI, smoking, and history of secondary atherosclerosis.
Conclusions: Increased ICA-PI was associated with a high total SVD score in acute small-vessel occlusion and may be an alternative method for predicting the total SVD score, enabling the administration of interventions to prevent stroke relapse without the need for MRI.
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| http://dx.doi.org/10.1016/j.clineuro.2024.108127 | DOI Listing |
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