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Low incidence of pancreatic fistula and well-preserved endocrine function with non-reconstructed small remnant pancreas after pancreaticoduodenectomy.
Ann Gastroenterol Surg
September 2024
Aim: Pancreatic reconstruction after pancreaticoduodenectomy (PD) that leaves a small remnant pancreas is often difficult. Pancreatic fistula is a major complication after PD, and fistulas are rare in patients with hard pancreas. However, the clinical impact of non-reconstructed small remnant after PD with hard pancreas is unknown.
View Article and Find Full Text PDFNot just a BLiP: early experience with a novel multidisciplinary case conference for benign hepatopancreatobiliary disease at a tertiary Canadian healthcare center.
Surg Endosc
December 2024
Division of General Surgery, Western University, London, ON, Canada.
Background: Benign Liver and Pancreas (BLiPs) rounds, implemented in 2022 at our Canadian tertiary care center, are a novel concept of a multidisciplinary case conference (MCC) for discussion of benign hepatopancreatobiliary (HPB) disease. BLiPs Rounds are a monthly virtual meeting of surgeons, gastroenterologists, and interventional radiologists experienced in biliary and pancreatic disease.
Methods: This case series was completed to review the patient cases discussed over the first year of BLiPs rounds, and to evaluate the effect of the multidisciplinary discussion on patient management plans.
[Clinicopathological features of BAP1 mutated clear cell renal cell carcinoma].
Zhonghua Bing Li Xue Za Zhi
August 2024
Department of Pathology, the First Affiliated Hospital, Zhejiang University School of Medicine,Hangzhou 310003, China.
To investigate the clinicopathological characteristics, immunophenotypes, molecular features, and differential diagnosis of BAP1 mutated clear cell renal cell carcinoma (CCRCC) for better understanding this entity. Clinical data, histological morphology, immunophenotypes and molecular characteristics of 18 BAP1 mutated CCRCC cases diagnosed at the Department of Pathology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China from January 2020 to December 2022 were analyzed. The patients were followed up.
View Article and Find Full Text PDFArticle Synopsis
- The study evaluated the use of endoscopic ultrasound-guided tissue acquisition (EUS-TA) with a 22-gauge Franseen needle for collecting tissue samples from solid tumors, focusing on its application in comprehensive genomic profiling (CGP) tests, especially for pancreatobiliary cancer.
- A total of 50 patients were analyzed, showing that the success rates for obtaining suitable samples for CGP were 86% and 76% through two quality control checks, with an adverse event rate of 4%.
- The findings indicated that while EUS-TA using this method is feasible, a significant portion of the specimens did not meet CGP criteria, raising questions about sample adequacy for genomic analysis despite successful tests.
Metastatic clear cell sarcoma of the pancreas: A rare case report.
World J Clin Cases
March 2024
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Soochow University, Suzhou 215008, Jiangsu Province, China.
Background: Clear cell sarcoma (CCS) is a rare soft-tissue sarcoma. The most common metastatic sites for CCS are the lungs, bones and brain. CCS is highly invasive and mainly metastasizes to the lung, followed by the bone and brain; however, pancreatic metastasis is relatively rare.
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