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Potential Strategies Applied by to Survive the Immunity of Its Crustacean Hosts.
Pathogens
January 2025
Key Laboratory of Zoonosis of Liaoning Province, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang 110866, China.
is the specific pathogen for "milky disease" in the Chinese mitten crab (), accounting for huge losses to the industry. And yet, there is no precise study describing the pathogenesis of , largely hindering the development of novel control methods against its causing diseases. Here, we compared the transcriptomes of cells collected from a control group (cultured without hemocytes) and a treatment group (cultured with hemocytes), using RNA sequencing.
View Article and Find Full Text PDFEvolving Trends and Patterns of Utilization of Magnetic Resonance-Guided Radiotherapy at a Single Institution, 2018-2024.
Cancers (Basel)
January 2025
Department of Radiation Oncology, Miami Cancer Institute, Miami, FL 33176, USA.
: Over the past decade, significant advances have been made in image-guided radiotherapy (RT) particularly with the introduction of magnetic resonance (MR)-guided radiotherapy (MRgRT). However, the optimal clinical applications of MRgRT are still evolving. The intent of this analysis was to describe our institutional MRgRT utilization patterns and evolution therein, specifically as an early adopter within a center endowed with multiple other technology platforms.
View Article and Find Full Text PDFSingle-stage intramedullary nailing for patients with multiple concurrent long-bone fractures in a low-resource setting: what factors contribute to prolonged operative duration?
Eur J Trauma Emerg Surg
January 2025
Bowen University Teaching Hospital, P. O. Box 15, Ogbomoso, Oyo State, Nigeria.
Purpose: To investigate the factors that prolonged the operative duration (OD) in patients who underwent single-stage locked intramedullary nailing of their multiple concurrent long-bone fractures (LBFs) using Surgical Implant Generation Network (SIGN) nails.
Methods: Forty-nine patients who fulfilled the inclusion criteria were enrolled prospectively over 8½ years. Data collected included age, sex, injury mechanism and severity, fracture characteristics, nail types and diameter, OD, fracture-to-fixation time, length of hospital stay (LOS), functional outcomes and complications.
Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction.
Mol Oncol
January 2025
Center for Molecular Medicine, MaineHealth Institute for Research, Scarborough, ME, USA.
Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5-year survival rate of 59%. Dysregulation of fatty acid (FA) metabolism is associated with MM development and progression; however, the underlying mechanisms remain unclear. Herein, we explore the roles of long-chain fatty acid coenzyme A ligase (ACSL) family members in MM.
View Article and Find Full Text PDFEffects of osteosynthesis of the bony thorax in the context of polytrauma compared to conservative treatment: a systematic review.
Eur J Trauma Emerg Surg
January 2025
Department of Intensive Care Medicine and Intermediate Care Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074, Aachen, Germany.
Purpose: Osteosynthesis seems to have effects regarding clinical outcomes in trauma patients. However, current knowledge on chest wall osteosynthesis in polytrauma patients is insufficient, leaving its potential unanswered. Therefore, the objective of this systematic review is to assess the safety and effects of chest wall osteosynthesis compared to conservative treatment on clinical outcomes in adult polytrauma patients.
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