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Comparative label-free proteomics of the neonatal meningitis-causing K1 IHE3034 and RS218 morphotypes. | LitMetric
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Comparative label-free proteomics of the neonatal meningitis-causing K1 IHE3034 and RS218 morphotypes.

Nikola Zlatkov Wilma Gunnari Ulrike Resch

Microbiol Resour Announc

Department of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

Published: February 2024

The proteome of two newborn meningitis K1 (NMEC) morphotypes was examined via a label-free proteomics approach. Besides shared NMEC virulence factors, the two strains have different evolutionary strategies-strain IHE3034 tends to perform anaerobic respiration continuously, while strain RS218 maintains its filamentous morphotype due to active SOS response.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10868230PMC
http://dx.doi.org/10.1128/mra.00960-23DOI Listing

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