Two new styryl lactone derivatives, goniothapic acids A () and B (), and 18 known compounds, were isolated from the twig and leaf extracts of Miq. The structures of new compounds were characterised by spectroscopic methods and HRESITOFMS. Their absolute configuration was established by comparing the experimental and calculated ECD spectra. Eleven compounds were evaluated for their α-glucosidase inhibitory activity. Of these, (-)-goniothalamin () and oldhamactam () showed the best α-glucosidase inhibitory activity with IC values of 54.8 and 57.9 µM, respectively.

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http://dx.doi.org/10.1080/14786419.2024.2306172DOI Listing

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