Objective: Hypercementosis (HPC) is an asymptomatic pathology that, according to the existing literature, has a low prevalence, there is a lack of information and research on it, within these studies, few are made by ethnic groups. To determine the prevalence and radiographic patterns of this condition, as well as the analysis of the relationship of the pathology with some of what are considered possible local triggering factors (FDL) in Mexican individuals.
Methodology: 1193 orthopantomographies (OPG) were analyzed, randomly selected from patients of both sexes, with a chronological age range between 18 and 90 years, identifying the prevalence of HPC, as well as its relationship between age groups, its morphological patterns (focal, diffuse and sleeve-shaped), its distribution by anatomical region and dental organs (ODs) and the association of its presence with possible local triggering factors.
Results: 348 DO with HPC were found in a total of 194 patients (16.30%), with no relevant differences between genders (P> 0.05). There was a significant increase with respect to the presence of HPC in relation to the increase in the age of the patients (P= 0.001), finding it present in 10% of the age group <40 years, in 20.30% in the group of 40 to 60 years and > 60 in 30.20%. It was found more frequently in a diffuse form (75.28%), followed by the focal pattern (19.54%) and finding the sleeve-shaped morphology less common (5.17%). The mandible presented the greatest number of ODs with the presence of HPC, 136 (39.08%), with the left side being the most affected with 86 OD. The dental group with the greatest involvement was that of molars and premolars.
Conclusions: The prevalence of hypercementosis was 16.30% in the Mexican individuals evaluated. Its presence increases as the age of the patients advances. Its main location is the mandibular region with a predilection for premolars and molars. Even though the idiopathic origin is the most frequent, it was observed that dental impaction is a possible local triggering factor.
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http://dx.doi.org/10.21142/2523-2754-1103-2023-163 | DOI Listing |
Dev Cell
January 2025
Umeå Plant Science Centre (UPSC), Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, 901 83 Umeå, Sweden. Electronic address:
Reactivation of cell division is crucial for the regeneration of damaged tissues, which is a fundamental process across all multicellular organisms. However, the mechanisms underlying the activation of cell division in plants during regeneration remain poorly understood. Here, we show that single-cell endodermal ablation generates a transient change in the local mechanical pressure on neighboring pericycle cells to activate patterned cell division that is crucial for tissue regeneration in Arabidopsis roots.
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January 2025
Department of Neuroscience, City University of Hong Kong, Kowloon, Hong Kong.
High-frequency stimulation (HFS)-induced long-term potentiation (LTP) is generally regarded as a homosynaptic Hebbian-type LTP, where synaptic changes are thought to occur at the synapses that project from the stimulation site and terminate onto the neurons at the recording site. In this study, we first investigated HFS-induced LTP on urethane-anesthetized rats and found that cortical HFS enhances neural responses at the recording site through the strengthening of local connectivity with nearby neurons at the stimulation site, rather than through synaptic strengthening at the recording site. This enhanced local connectivity at the stimulation site leads to increased output propagation, resulting in signal potentiation at the recording site.
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November 2024
Division of Pediatric Immunology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Background: Griscelli syndrome (GS) is a rare genetic disorder characterized by oculocutaneous albinism and variable immune dysfunction. Among three distinct types of GS, occurring due to different genetic mutations; GS type 1 presents with neurological manifestations, hemophagocytic lymphohistiocytosis (HLH) generally develops in GS type 2, and GS type 3 primarily exhibits oculocutaneous albinism. HLH, a life-threatening condition with excessive immune activation, may occur secondary to various triggers, including infections, and develop in different tissues, as well as in the testis, similar to Erdheim-Chester disease.
View Article and Find Full Text PDFSmall
January 2025
Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawinskiego 5B Str., Warsaw, 02-106, Poland.
The urea oxidation reaction (UOR) is characterized by a lower overpotential compared to the oxygen evolution reaction (OER) during electrolysis, which facilitates the hydrogen evolution reaction (HER) at the cathode. Charge distribution, which can be modulated by the introduction of a heterostructure, plays a key role in enhancing the adsorption and cleavage of chemical groups within urea molecules. Herein, a facile all-room temperature synthesis of functional heterojunction NiCoS/CoMoS grown on carbon cloth (CC) is presented, and the as-prepared electrode served as a catalyst for simultaneous hydrogen evolution and urea oxidation reaction.
View Article and Find Full Text PDFAdv Healthc Mater
January 2025
Department of Pharmaceutics, School of Pharmacy, Qingdao University, Qingdao, 266071, China.
In situ tumor vaccines, which utilize antigens generated during tumor treatment to stimulate a cancer patient's immune system, has become a potential field in cancer immunotherapy. However, due to the immunosuppressive tumor microenvironment (ITME), the generation of tumor antigens is always mild and not sufficient. Tumor-resident intracellular bacteria have been identified as a complete tumor microenvironment component to contribute to creating ITME.
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