A Case of Eosinophilic Pustular Folliculitis Misdiagnosed as Eczema.

Clin Cosmet Investig Dermatol

Department of Cosmetic Dermatology, The Fifth People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.

Published: January 2024

AI Article Synopsis

  • - Eosinophilic pustular folliculitis (EPF) is a rare skin condition, often misdiagnosed, where lesions appear primarily on the upper limbs, face, and trunk, but can initially show up on palms and soles.
  • - A male patient, misdiagnosed with eczema for ten years, experienced recurring skin issues and had a biopsy that confirmed EPF due to eosinophilic infiltrates in hair follicles.
  • - Treatment with 75mg/day of oral indomethacin led to complete resolution of his skin lesions, with no recurrence noted after three months.

Article Abstract

Eosinophilic pustular folliculitis (EPF) is a rare skin disease. The typical skin lesions of classic EPF are localized on the upper limbs' face, trunk, and extensor surfaces. However, when the skin lesions initially appear on the palms and soles, it is not easy to diagnose as EPF. Here, we report a case of a male patient who presented with erythematous plaques, pustules, and crusted erosions on the hands and feet, which were misdiagnosed as eczema ten years ago. Over ten years, the patient experienced recurrent erythematous patches with bumps and itching on the face, trunk, and extremities after improving the hand and foot lesions. A histopathological biopsy was performed to establish a definitive diagnosis, revealing pustules formed by eosinophilic infiltrates within the hair follicles. The diagnosis was confirmed as eosinophilic pustular folliculitis. The patient was treated with oral indomethacin at a dosage of 75mg/day, resulting in the disappearance of the skin lesions. After a 3-month follow-up, no recurrence was observed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10822092PMC
http://dx.doi.org/10.2147/CCID.S445760DOI Listing

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