AI Article Synopsis

  • Non-alcoholic fatty liver disease (NAFLD) is increasingly linked to type 2 diabetes and obesity, becoming a significant health issue worldwide.
  • A systematic review of studies in Saudi Arabia found that 47.8% to 72.8% of diabetes patients surveyed had NAFLD, indicating a serious prevalence concern.
  • The analysis highlights the need for improved public health strategies in Saudi Arabia to detect and manage NAFLD effectively, especially since there was a high variability in the studies' findings.

Article Abstract

Non-alcoholic fatty liver disease (NAFLD) is a burgeoning global health concern, closely associated with the rising prevalence of type 2 diabetes mellitus (T2DM) and obesity. This systematic review and meta-analysis aim to comprehensively evaluate the prevalence of NAFLD in DM patients in Saudi Arabia, a country undergoing rapid socioeconomic changes. Our multifaceted search strategy identified four high-quality studies conducted between 2003 and 2022, covering hospital and community settings. The aggregate prevalence rate of NAFLD in DM patients was notably high, ranging from 47.8% to 72.8%. However, substantial heterogeneity (I² = 90.6%) was observed, indicating variability attributed to diverse study characteristics. The uniform application of ultrasound for diagnosis was noteworthy but raised concerns regarding sensitivity. This analysis underscores the urgency of public health measures for early detection and management of NAFLD in DM-prone populations in Saudi Arabia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10810724PMC
http://dx.doi.org/10.7759/cureus.51092DOI Listing

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