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Differential diagnostics of food allergy as based on provocation tests and laboratory diagnostic assays. | LitMetric

AI Article Synopsis

  • Food allergies are a major health concern that greatly affect patients' quality of life.
  • Diagnostic methods include skin tests, specific IgE detection, and food challenges, which are considered the best approaches for determining food allergies.
  • There is growing interest in nasal provocation tests as a diagnostic tool, but factors like allergen dosage and standardized protocols are crucial for their effectiveness.

Article Abstract

Due to the scale of the phenomenon, food allergy constitute a significant health problem and significantly impair the quality of life of patients. Differential diagnostics, including skin tests, sIgE detection tests, basophil and mast cell activation tests as well as double-blind placebo-controlled food challenge tests, is the gold standard in the diagnosis of food allergy. Recently, increasing attention has been paid to the potential use of nasal provocation test in the diagnosis of food allergy. Allergen dose, protocol standardization, assessment of subjective complaints and objectivization of test results are important factors determining the applicability of provocation tests.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10809836PMC
http://dx.doi.org/10.5114/ada.2023.132501DOI Listing

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