Objectives: We evaluated the completeness of real-world Focused Assessment with Sonography for Trauma (FAST) in children after blunt abdominal trauma by benchmarking against established expert guidelines.
Methods: We conducted a retrospective cohort study, analyzing a random sample of FASTs from two urban pediatric emergency departments. Two experts reviewed and labeled all FASTs for completeness using a predefined guideline of 5 anatomic views and 30 landmarks. We compared frequencies of views and landmarks as medians with interquartile ranges.
Results: We analyzed 200 FASTs, consisting of 1636 video clips, performed by 31 clinicians representing 198 children with a median age of 10 years (IQR 5,14). Over half of FASTs (52%) had all 5 views. The right upper quadrant view was most commonly visualized (96.5%), and suprapubic sagittal was least (65%). None of the FASTs included all 30 landmarks, ranging from 0 to 28 and median of 19 (IQR 15,23). The least visualized landmark of the right and left upper quadrants was caudal liver edge (60%) and splenic tip (64%), respectively. In the pericardial view, it was left atrium (45%). In both transverse and sagittal pelvic views, retro-uterine space was least visualized in girls, 21 and 29% respectively.
Conclusions: In our study, most FAST views and landmarks were visualized. However, the pelvic sagittal view was the least frequently visualized view, and caudal liver edge was the least visualized landmark. Future research should evaluate if variability in visualizing FAST views and landmarks correlates with inconsistencies in diagnostic test performance.
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http://dx.doi.org/10.1002/jum.16417 | DOI Listing |
Front Biosci (Landmark Ed)
November 2024
Department of Life Sciences, School of Life and Health Sciences, University of Nicosia, 2417 Nicosia, Cyprus.
The Warburg effect, also known as 'aerobic' glycolysis, describes the preference of cancer cells to favor glycolysis over oxidative phosphorylation for energy (adenosine triphosphate-ATP) production, despite having high amounts of oxygen and fully active mitochondria, a phenomenon first identified by Otto Warburg. This metabolic pathway is traditionally viewed as a hallmark of cancer, supporting rapid growth and proliferation by supplying energy and biosynthetic precursors. However, emerging research indicates that the Warburg effect is not just a strategy for cancer cells to proliferate at higher rates compared to normal cells; thus, it should not be considered an 'enemy' since it also plays complex roles in normal cellular functions and/or under stress conditions, prompting a reconsideration of its purely detrimental characterization.
View Article and Find Full Text PDFBiol Open
December 2024
School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Wits 2050, Johannesburg, Gauteng 2000, South Africa.
Felid bone morphology is highly influenced by factors such as locomotion, body size, and foraging behaviour. Understanding how these factors influence bone morphology is important for interpreting the behaviour and ecology of such species. This study aimed to determine the extent to which Panthera pardus (i.
View Article and Find Full Text PDFTwo key series of discoveries about the hippocampus are described. One is the discovery of hippocampal spatial view cells in primates. This discovery opens the way to a much better understanding of human episodic memory, for episodic memory prototypically involves a memory of where people or objects or rewards have been seen in locations "out there" which could never be implemented by the place cells that encode the location of a rat or mouse.
View Article and Find Full Text PDFAnn Surg Oncol
December 2024
Surgery, Phoenix Indian Medical Center, Phoenix, AZ, USA.
American Indian and Alaska Natives (AI/ANs) are a heterogeneous group of people living throughout the USA with some of the highest cancer incidence and highest cancer-related mortality in the country. This landmark series seeks to highlight cancer care in this population by providing a historical context of the largest healthcare delivery system serving AI/ANs, the Indian Health Service (IHS). We will highlight how the dynamic nature of this population creates unique challenges and the need for dedicated resources to help eliminate cancer care disparities.
View Article and Find Full Text PDFJ Hand Surg Am
December 2024
Division of Plastic and Reconstructive Surgery, Department of Surgery, Western University, London, Ontario, Canada.
Purpose: This study aimed to determine the reliability and concurrent validity of finger joint range of motion (ROM) measurement using augmented reality (AR)-based hand tracking in a sample of healthy hands. Additionally, the study aimed to determine which camera view of the hand provided ROM measurements with the highest concurrent validity at each joint.
Methods: A web application developed for smart devices using Google's MediaPipe Hands framework converted AR-generated hand landmark coordinates from camera feed into ROM angle measurements in real time for all joints.
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