The cardiovascular and neuroendocrine effects of a high-dose fentanyl anaesthesia (100 micrograms/kg body weight) were compared with those of a balanced type of fentanyl anaesthesia (5 micrograms kg-1) during upper abdominal surgery. High-dose fentanyl anaesthesia prevented the increase in catecholamine concentrations and attenuated the circulatory response to surgical stress seen in the group anaesthetized with the balanced technique of anaesthesia.
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| http://dx.doi.org/10.1093/bja/59.2.184 | DOI Listing |
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