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AGA Clinical Practice Update on Screening and Surveillance in Individuals at Increased Risk for Gastric Cancer in the United States: Expert Review.
Gastroenterology
December 2024
Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, California.
Description: Gastric cancer (GC) is a leading cause of preventable cancer and mortality in certain US populations. The most impactful way to reduce GC mortality is via primary prevention, namely Helicobacter pylori eradication, and secondary prevention, namely endoscopic screening and surveillance of precancerous conditions, such as gastric intestinal metaplasia (GIM). An emerging body of evidence supports the possible impact of these strategies on GC incidence and mortality in identifiable high-risk populations in the United States.
View Article and Find Full Text PDFAttenuation of Pathway Complexity in Arginine-Rich Peptide with Polydopamine.
Small
December 2024
Chemical Biology Unit, Institute of Nano Science and Technology (INST), Sector 81, Mohali, Punjab, 140306, India.
Dynamic peptide networks represent an attractive structural space of supramolecular polymers in the realm of emergent complexity. Point mutations in the peptide sequence exert profound effects over the landscapes of self-assembly with an intricate interplay among the structure-function relationships. Herein, the pathway complexity of an arginine-rich peptide is studied, FmocVFFARR derived by the mutation of minimalist amyloid-inspired peptide amphiphile FmocVFFAKK, thereby focusing on its pathway-dependent self-assembly behavior.
View Article and Find Full Text PDFThe authors present a case of a distal phalanx fracture secondary to a nail gun injury. The diagnosis, evaluation and emergency departmetn treatment are reviewed.
View Article and Find Full Text PDFCatalyzing Pharmacogenomic Analysis for Informing Pain Treatment (C-PAIN): A Randomized Trial of Preemptive Genotyping in Cancer Palliative Care.
J Pain Res
December 2024
Committee on Clinical Pharmacology and Pharmacogenomics, University of Chicago, Chicago, IL, USA.
Background: Cancer patients frequently suffer from pain, often managed with opioids. However, undertreated pain remains a significant concern. Opioid effectiveness varies due to genetic differences in how individuals metabolize some of these medications.
View Article and Find Full Text PDFFrom risk to reward: Unveiling the multidimensional impact of financial risks on the performance of Ghanaian banks.
Heliyon
December 2024
School of Accounting, Zhongnan University of Economics and Law, Wuhan, China.
The Ghanaian banking sector, grappling with a spectrum of financial risks, presents a compelling case study for understanding the dynamics of risk and profitability in emerging markets. This study seeks to fortify the financial performance of Ghanaian banks through an innovative application of benchmark regression analysis, focusing on critical financial risk and performance metrics. Employing an explanatory research methodology, we harnessed a panel regression model to scrutinize secondary data extracted from the annual income statements of 23 banks, spanning nearly two decades from 2006 to 2023.
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