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Self-assembled peptide hydrogels for the treatment of diabetes and associated complications. | LitMetric

Self-assembled peptide hydrogels for the treatment of diabetes and associated complications.

Colloids Surf B Biointerfaces

Institute for Health and Sport, Victoria University, Melbourne, VIC, Australia; Immunology Program, Australian Institute for Musculoskeletal Science, Melbourne, VIC, Australia. Electronic address:

Published: March 2024

AI Article Synopsis

Article Abstract

Diabetes is a widespread epidemic that includes a number of comorbid conditions that greatly increase the chance of acquiring other chronic illnesses. Every year, there are significantly more people with diabetes because of the rise in type-2 diabetes prevalence. The primary causes of illness and mortality worldwide are, among these, hyperglycemia and its comorbidities. There has been a lot of interest in the creation of peptide-based hydrogels as a potentially effective platform for the treatment of diabetes and its consequences. Here, we emphasize the use of self-assembled hydrogel formulations and their unique potential for the treatment/management of type-2 diabetes and its consequences. (i.e., wounds). Key aspects covered include the characteristics of self-assembled peptide hydrogels, methods for their preparation, and their pre-clinical and clinical applications in addressing metabolic disorders such as type-2 diabetes.

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Source
http://dx.doi.org/10.1016/j.colsurfb.2024.113761DOI Listing

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