Aims: The antihypertensive activity of was tested.
Background: (Thymelaeaceae) is used against hypertension.
Objective: The antihypertensive effect of was evaluated in this study.
Methods: The effect of aqueous extract (DGAE, 100 and 180 mg/kg) on blood pressure was evaluated in rats. In addition, the vasorelaxant effect of this extract was also tested.
Results: DGAE lowered blood pressure in hypertensive rats and exhibited vasorelaxant activity. In addition, cumulative concentrations of DGAE induced vasodilatation through receptoractivated calcium channels (ROCCs) without affecting ACE-2.
Conclusion: The aqueous extract of exhibits antihypertensive activity and induces vasodilatation via the inhibition of Ca entry.
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