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Mining and analysis of adverse events profile of Guanfacine using FDA Adverse Event Reporting System (FAERS) database.
Expert Opin Drug Saf
December 2024
Department of Pediatrics, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Objective: This study aims to evaluate the Guanfacine-associated adverse events (AEs) in real-world using data mining in FAERS database, seeking to provide safety profile and guidance for the potential therapeutic practices.
Methods: We retrospectively extracted Guanfacine-associated AEs reports in the FAERS database from the first quarter of 2004 (Q1) to the fourth quarter of 2023 (Q4). All data were strictly collected and comprehensively analyzed.
Alcohol Dependence Among Adult Males in Chengalpattu District, South India: A Mixed Methods Study.
Cureus
August 2024
Preventive Medicine, Dr. MGR Educational and Research University, Chennai, IND.
Introduction Post-pandemic alcohol consumption is on the rise due to people starting to adapt themselves to the practice of consuming alcoholic beverages at home. In addition to the direct effects of intoxication and addiction, estimates suggest that alcohol contributes to approximately 20-30% of global cases of oesophagal cancer, liver cancer, cirrhosis of the liver, homicide, epilepsy, and motor vehicle accidents. In India, one-fifth of alcohol consumers were found to be alcohol dependent.
View Article and Find Full Text PDFRefractory Homicidal Ideation in a Young Adult Male With High-Functioning Autism Spectrum Disorder and Schizophrenia.
Cureus
July 2024
Department of Psychiatry, Hospital Corporation of America (HCA) Florida Orange Park Hospital, Orange Park, USA.
Persistent homicidal ideation (HI), while not common among psychiatric disorders, can occur within multiple diagnoses in the Diagnostic and Statistical Manual of Mental Disorders. There is a growing global and national concern for homicide and homicide-related deaths. In this case report, we discuss refractory homicidal ideation in an 18-year-old male with the diagnoses of autism spectrum disorder (ASD) and schizophrenia and a history of Tourette's syndrome and highlight the interplay of comorbidities and challenges in effective management and treatment.
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