Currently, groin hernia repair is mostly performed with application of mesh prostheses fixed with or without suture. However, views on safety and efficacy of different surgical approaches are still partly discordant. In this multicentre retrospective study, three sutureless procedures, i.e., mesh fixation with glue, application of self-gripping mesh, and Trabucco's technique, were compared in 1034 patients with primary unilateral non-complicated inguinal hernia subjected to open anterior surgery. Patient-related features, comorbidities, and drugs potentially affecting the intervention outcomes were also examined. The incidence of postoperative complications, acute and chronic pain, and time until discharge were assessed. A multivariate logistic regression was used to compare the odds ratio of the surgical techniques adjusting for other risk factors. The application of standard/heavy mesh, performed in the Trabucco's technique, was found to significantly increase the odds ratio of hematomas ( = 0.014) and, most notably, of acute postoperative pain ( < 0.001). Among the clinical parameters, antithrombotic therapy and large hernia size were independent risk factors for hematomas and longer hospital stay, whilst small hernias were an independent predictor of pain. Overall, our findings suggest that the Trabucco's technique should not be preferred in patients with a large hernia and on antithrombotic therapy.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10816828 | PMC |
http://dx.doi.org/10.3390/jcm13020589 | DOI Listing |
Oncol Ther
November 2024
Oncology Unit, "Andrea Tortora" Hospital, ASL Salerno, Pagani, Italy.
Eur J Obstet Gynecol Reprod Biol
December 2024
IVIRMA Global Research Alliance, Genera, Clinica Valle Giulia, Rome, Italy.
Objective: To compare DuoStim versus a conventional approach in patients indicated to Preimplantation-Genetic-Testing for both monogenic conditions and aneuploidies (PGT-M + PGT-A).
Study Design: Retrospective case-control study. In 5 years, 132 couples indicated to PGT-M + PGT-A who obtained ≤5 blastocysts after a first retrieval were suggested to undergo a second stimulation in the same ovarian cycle.
Plants (Basel)
October 2024
Department of Life Sciences, University of Trieste, 34127 Trieste, Italy.
Digitization of Natural History Collections (NHCs) and mobilization of their data are pivotal for their study, preservation, and accessibility. Furthermore, thanks to digitization and mobilization, Natural History Museums can better showcase their collections, potentially attracting more visitors. However, the optimization of digitization workflows, especially when addressing small and/or historical NHCs, remains a challenge.
View Article and Find Full Text PDFJ Pers Med
September 2024
Department of Urology, Medical Institute, St. Petersburg University, Mendeleevskaya Line 2, 197036 St. Petersburg, Russia.
Introduction: Melatonin and serotonin can influence certain aging processes in the ovaries. The main melatonin receptors are represented by types MT1 and MT2. The goal of investigation.
View Article and Find Full Text PDFSmall
November 2024
Terasaki Institute for Biomedical Innovation, 21100 Erwin St, Woodland Hills, CA, 91367, USA.
Drug toxicity assays using conventional 2D static cultures and animal studies have limitations preventing the translation of potential drugs to the clinic. The recent development of organs-on-a-chip platforms provides promising alternatives for drug toxicity/screening assays. However, most studies conducted with these platforms only utilize single endpoint results, which do not provide real-time/ near real-time information.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!