AI Article Synopsis

  • Sodium nitroprusside and its adenine complex slow down the growth of E. coli cultures and the adenine complex also kills the bacteria.
  • The adenine complex did not cause base-pair mutations in E. coli during mutation experiments.
  • However, it's still possible that it could induce other types of mutations that weren't tested.

Article Abstract

Sodium nitroprusside and its adenine complex were found to decrease the growth rate of exponentially growing Escherichia coli cultures, and the adenine complex to exert in addition a bactericidal effect. In mutation experiments the latter compound failed to induce base-pair substitutions in the E. coli strains tested but the results do not allow to exclude other mutagenic mechanisms.

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