Breast cancer (BC) is the leading cause of mortality among women across the world. Earlier screening of BC can significantly reduce the mortality rate and assist the diagnostic process to increase the survival rate. Researchers employ deep learning (DL) techniques to detect BC using mammogram images. However, these techniques are resource-intensive, leading to implementation complexities in real-life environments. The performance of convolutional neural network (CNN) models depends on the quality of mammogram images. Thus, this study aimed to build a model to detect BC using a DL technique. Image preprocessing techniques were used to enhance image quality. The authors developed a CNN model using the EfficientNet B7 model's weights to extract the image features. Multi-class classification of BC images was performed using the LightGBM model. The Optuna algorithm was used to fine-tune LightGBM for image classification. In addition, a quantization-aware training (QAT) strategy was followed to implement the proposed model in a resource-constrained environment. The authors generalized the proposed model using the CBIS-DDSM and CMMD datasets. Additionally, they combined these two datasets to ensure the model's generalizability to diverse images. The experimental findings revealed that the suggested BC detection model produced a promising result. The proposed BC detection model obtained an accuracy of 99.4%, 99.9%, and 97.0%, and Kappa (K) values of 96.9%, 96.9%, and 94.1% in the CBIS-DDSM, CMMD, and combined datasets. The recommended model streamlined the BC detection process in order to achieve an exceptional outcome. It can be deployed in a real-life environment to support physicians in making effective decisions. Graph convolutional networks can be used to improve the performance of the proposed model.
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http://dx.doi.org/10.3390/diagnostics14020227 | DOI Listing |
ISA Trans
January 2025
Department of Electrical and Computer Engineering, National University of Singapore, 117538, Singapore. Electronic address:
For tolerant containment control of multi-agent systems, considering the challenges in modeling and the impact of actuator faults on system security and reliability, a finite index dynamic event-triggered policy iteration algorithm is proposed. This algorithm only requires input and output data, without relying on system models, and simultaneously considers the faults and energy consumption issues to improve the system reliability and save energy consumption. The conditions are provided to demonstrate the convergence and optimality of the algorithm, including a convergence speed, that is, the number of iterations required for convergence is finite.
View Article and Find Full Text PDFSurv Ophthalmol
January 2025
Centre for Ocular Regeneration (CORE), L V Prasad Eye Institute, Hyderabad, Telangana, India; Prof. Krothapalli Ravindranath Ophthalmic Research Biorepository, LV Prasad Eye Institute, Hyderabad, Telangana, India.
Extracellular vesicles (EVs), defined as membrane-bound vesicles released from all cells, are being explored for their diagnostic and therapeutic role in dry eye disease (DED). We systematically shortlisted 32 articles on the role of EVs in diagnosing and treating DED. The systematic review covers the progress in the last 2 decades about the classification and isolation of EVs and their role in DED.
View Article and Find Full Text PDFTheor Popul Biol
January 2025
Otto von Guericke University Magdeburg, Institute for Intelligent Cooperating Systems, Universitatsplatz 2, 39106, Sachsen-Anhalt, Germany.
Although extensively studied, the maintenance of biodiversity remains a highly debated and investigated topic of contemporary research in ecology. Several studies have quantified the contributions of various coexistence mechanisms to biodiversity. However, often stochastic individual-level interactions are abstracted away, or mechanisms are studied in isolation.
View Article and Find Full Text PDFNucl Med Biol
January 2025
State Research Center-Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, 123182 Moscow, Russia. Electronic address:
Introduction: Folate receptors (FR) have been considered a convenient target for different radiopharmaceuticals in recent years. Multifarious Ga-labeled folate conjugates have been proposed as promising agents for the PET imaging of FR-overexpressing malignant neoplasms. In addition, radiolabeled folate-based conjugates can be effective for imaging non-tumor pathological foci characterized by a pronounced cluster of activated macrophages.
View Article and Find Full Text PDFInt J Nurs Stud
January 2025
NIHR Collaboration for Applied Research (Wessex), University of Southampton, Southampton, United Kingdom. Electronic address:
Ongoing challenges in the provision of care, driven by growing care complexity and nursing shortages, prompt us to reconsider the basis for efficient division of nursing labour. In organising nursing work, traditionally the focus has been on identifying nursing tasks that can be delegated to other less expensive and less highly educated staff, in order to make best use of scarce resources. We argue that nursing care activities are connected and intertwined.
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