Background: As the field of probiotic research continues to expand, new beneficial strains are being discovered. The family and its newly described member, , have been shown to offer great health benefits. We aimed to extensively review the existing literature on these microorganisms to highlight the advantages of their use as probiotics and address some of the most challenging aspects of their commercial production and potential solutions.

Methods: We applied a simple search algorithm using the key words "" and "" to find all articles reporting the biotherapeutic effects of these microorganisms. Only articles reporting evidence-based results were reviewed.

Results: The review showed that has demonstrated numerous beneficial properties and a wider range of uses than previously thought. Moreover, it has been shown to be oxygen-tolerant, which is an immense advantage in the manufacturing and production of -based biotherapeutics. The results suggest that and specifically can play a crucial role in maintaining a healthy gut microbiome. Furthermore, have been associated with weight management. Preliminary studies suggest that this probiotic strain could have a positive impact on metabolic disorders like diabetes and obesity, as well as inflammatory bowel disease.

Conclusion: and specifically offer immense health benefits and could be used in the management and therapy of a wide range of health conditions. In addition to the impressive biotherapeutic effect, is oxygen-tolerant, which facilitates commercial production and storage.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10808311PMC
http://dx.doi.org/10.3389/fmicb.2023.1241259DOI Listing

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