AI Article Synopsis

  • * Researchers identified seven phenolic compounds in canola meal extract (CME) that contribute to its antioxidant capacity using advanced mass spectrometry techniques.
  • * When tested on human skin cells, CME significantly reduced damage from UV exposure and promoted collagen production, indicating its effectiveness as a functional food ingredient for skin health.

Article Abstract

Canola meal, a by-product of canola oil processing, is a source of bioactive compounds that show antioxidant and skin anti-aging effects through upcycling (i.e., creative reuse). Here we describe the antioxidant and skin anti-aging effects of canola meal extract (CME) obtained by upcycling canola meal. The antioxidant capacity of CME is due in part to its antioxidative phenolics. Seven phenolics, including sinapine and sinapic acid, in CME were identified using ultra-high-performance liquid chromatography-Orbitrap mass spectrometry. Addition of CME (1000 μg/mL) to human dermal fibroblast neonatal cells  significantly ( < 0.05) reduced matrix metalloproteinase-12 production and increased pro-collagen Ι alpha 1 content in response to ultraviolet B-induced oxidative stress compared with cells without CME. These results suggest that CME can serve as a functional food ingredient with antioxidant capacity and anti-aging effects on the skin.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805684PMC
http://dx.doi.org/10.1007/s10068-023-01379-xDOI Listing

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