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Molecular baskets form inclusion complexes with phenethylamine drugs in water. | LitMetric

Molecular baskets form inclusion complexes with phenethylamine drugs in water.

Chem Commun (Camb)

The Ohio State University, Department of Chemistry & Biochemistry, 100 W 18th Avenue, Columbus, OH 43210, USA.

Published: February 2024

Molecular basket 1 comprising a nonpolar cavity and an anionic nest of six carboxylates at its rim was found to form inclusion complexes with (1, 2)-ephedrine, (1, 2)-pseudoephedrine, and (1, 2)-tranylcypromine. Experimental results (NMR) and theory (MM/DFT) suggest the basket encapsulates phenethylamines in unique and predictable fashion.

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Source
http://dx.doi.org/10.1039/d3cc05485cDOI Listing

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