AI Article Synopsis
- Metabolic and cardiovascular diseases lead to a significant number of deaths and increase in morbidity, with effective primary prevention strategies like smoking cessation, weight management, and exercise recommended.
- The study analyzed biochemical and anthropometric data of 140 individuals in the Bardejov district, finding notable differences in BNP, cholesterol, triglycerides, and glucose levels across age groups and between genders.
- Results indicated that older individuals showed a higher prevalence of risk factors for cardiovascular disease, highlighting an increased lifetime risk associated with differing burdens of biochemical and anthropometric factors.
Article Abstract
Objectives: Metabolic and cardiovascular diseases represent a significant and ever-increasing problem, accounting for nearly one-third of all deaths and leading to significant morbidity. Lifestyle changes, which introduce new risk factors for cardiovascular disease, are leading to an increase in the risk of cardiovascular disease worldwide. The burden of cardiovascular disease can be reduced by careful risk reduction, and as such, primary prevention is an important priority for all. There is strong consensus among international guidelines regarding the necessity of smoking cessation, weight optimization, and the importance of exercise, while guidelines differ slightly in their approach to hypertension and vary greatly in their approach to the optimal lipid profile, which remains a controversial issue.
Methods: The work is focused on the analysis of biochemical (glucose, cholesterol and triacylglycerols) and anthropometric (body mass index) parameters in selected probands (n = 140), including men (n = 70) and women (n = 70) in the Bardejov district. Probands were divided into groups depending on age (18-38, 39-50, 51-60, and over 61 years). For statistical evaluation, the program Statistica ver. 12 and ANOVA were used.
Results: The results of the study showed statistically significantly higher values of BMI, total cholesterol (TC), triacylglycerides (TG), and glucose (GLU) (p < 0.001) between men and women in the age groups (18-38 years, 39-50 years). In probands from the age group 51-60 years and over 61 years, we found a high level of cholesterol above the reference limit, but a significant difference between men and women was not confirmed. Correlation analysis confirmed the positive correlation between glucose and BMI.
Conclusion: Differences in risk-factor (e.g., biochemical and anthropometrics) burden translate into marked differences in the lifetime risk of cardiovascular disease. These differences are consistent across age groups.
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| http://dx.doi.org/10.21101/cejph.a7839 | DOI Listing |
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