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The Curious Case of the Disappearing Cancer.
Cureus
November 2024
Internal Medicine, Weiss Memorial Hospital, Chicago, USA.
Esophageal cancer, particularly squamous cell carcinoma, poses significant diagnostic challenges due to its aggressive nature and similarity to metaplastic tissue. Accurate diagnosis often requires multiple biopsies and vigilant surveillance, especially in high-risk individuals with conditions such as gastroesophageal reflux disease (GERD) and a history of smoking. We present a 66-year-old female patient with a history of severe GERD and smoking, who underwent routine endoscopy revealing a gastric cardia nodule.
View Article and Find Full Text PDFThe case against simplistic genetic explanations of evolution.
Development
October 2024
Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA 92093, USA.
Humans are curious to understand the causes of traits that distinguish us from other animals and that distinguish vastly different species from one another. We also have a proclivity for simple stories and sometimes tend toward seeking and accepting simple genetic explanations for large evolutionary shifts, even to a single gene. Here, I reveal how a biased expectation of mechanistic simplicity threads through the long history of evolutionary and developmental genetics.
View Article and Find Full Text PDFThe Banana Lady and Other Stories of Curious Behavior and Speech.
Cogn Behav Neurol
September 2024
Department of Neurology, Vanderbilt Medical Center North, Vanderbilt University, Nashville, Tennessee.
The origin of 2,5-dimethoxy-4-methylamphetamine (DOM, STP).
Drug Test Anal
December 2024
Alexander Shulgin Research Institute, Lafayette, California, USA.
The story of the 1967 appearance of the powerful psychedelic 2,5-dimethoxy-4-methylamphetamine (DOM, STP) commonly omits details and often includes hyperbole and inaccuracies. It is well known how and when the drug was first distributed to the public for free by Owsley Stanley, but the role that Alexander Shulgin played in providing that material is not as well understood. In the interest of transparency and historical accuracy, this article attempts to present an accurate account of this well-known but inadequately detailed event.
View Article and Find Full Text PDFThe Curious Story of Recurrent Guillain-Barré Syndrome; A Lot More to Know.
Indian J Pediatr
May 2024
Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), New Delhi, India.
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