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The pectoralis major myocutaneous pedicled flap-Its past and current practice in a dedicated microsurgery service. Review of the literature, and debunking controversies.
J Plast Reconstr Aesthet Surg
November 2024
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan; Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan. Electronic address:
Background: The pectoralis major myocutaneous pedicled (PMMP) flap is still considered by many a workhorse flap in head and neck (H&N) reconstruction, despite free flap surgery advancing. The authors aimed to examine this claim and associated myths and controversies by analyzing literature trends and revealing the role of the PMMP flap in a well-established microsurgery center.
Methods: The senior author's reconstructive H&N practice between 1995 and 2022 was reviewed to describe and critically judge primary and secondary PMMP flap decisions to provide invaluable lessons learned and debunk common controversies related to complex H&N reconstruction.
Long-Term Potentiation: The Accidental Discovery.
Hippocampus
January 2025
Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Long-term potentiation (LTP), is a type of synaptic plasticity now considered essential for learning and memory. Here I tell the story of how I accidentally discovered in 1966 in the laboratory of Per Andersen in Oslo, Norway, because I was not looking for it. It just emerged.
View Article and Find Full Text PDFQuest for optimal quantum resetting: Protocols for a particle on a chain.
Phys Rev E
September 2024
Department of Physics, Indian Institute of Technology Tirupati, Tirupati 517619, India.
In the classical context, it is well known that, sometimes, if a search does not find its target, it is better to start the process anew. This is known as resetting. The quantum counterpart of resetting also indicates speeding up the detection process by eliminating the dark states, i.
View Article and Find Full Text PDFLarge Language Model-Based Responses to Patients' In-Basket Messages.
JAMA Netw Open
July 2024
NYU Grossman School of Medicine, New York, New York.
Importance: Virtual patient-physician communications have increased since 2020 and negatively impacted primary care physician (PCP) well-being. Generative artificial intelligence (GenAI) drafts of patient messages could potentially reduce health care professional (HCP) workload and improve communication quality, but only if the drafts are considered useful.
Objectives: To assess PCPs' perceptions of GenAI drafts and to examine linguistic characteristics associated with equity and perceived empathy.
Lévy flights and Lévy walks under stochastic resetting.
Phys Rev E
April 2024
Institute of Theoretical Physics and Mark Kac Center for Complex Systems Research, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Łojasiewicza 11, 30-348 Kraków, Poland.
Stochastic resetting is a protocol of starting anew, which can be used to facilitate the escape kinetics. We demonstrate that restarting can accelerate the escape kinetics from a finite interval restricted by two absorbing boundaries also in the presence of heavy-tailed, Lévy-type, α-stable noise. However, the width of the domain where resetting is beneficial depends on the value of the stability index α determining the power-law decay of the jump length distribution.
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