AI Article Synopsis
- Pakistan has a high burden of sepsis, but there's a lack of comprehensive data and understanding about it, especially in low-middle-income countries (LMICs) like Pakistan.
- The main sources of sepsis in Pakistan are respiratory and urinary tract infections, mainly caused by gram-negative organisms, and the healthcare system struggles with delayed access and poor adherence to existing treatment guidelines.
- Addressing sepsis requires focused efforts on implementing cost-effective guidelines and better data collection to improve diagnosis, management, and overall patient outcomes.
Article Abstract
Pakistan is a low-middle-income country (LMIC) with a high burden of sepsis, yet there is a profound dearth of data regarding sepsis with no comprehensive review. In Pakistan, access to competent healthcare services is delayed and in places, often not available. Patients may present with sepsis after common community-acquired infections; the commonest sources of sepsis are the respiratory tract followed by the urinary tract. Gram-negative organisms are responsible for a large majority of cases of sepsis. Unfortunately, compliance with sepsis guidelines remains poor, and sepsis-related statistics do not seem to be improving significantly. Adult sepsis presents a significant burden on healthcare services, particularly in LMICs, and is a leading cause of morbidity and mortality. Many factors which affect outcomes and cost of care are amenable to prompt interventions. Consequently, there is a dire need to make concentrated efforts in implementing simple, cost-effective, and context-specific guidelines and monitoring strategies regarding the diagnosis and management of sepsis. The collection and analysis of information on sepsis in Pakistan hence remains imperative, in order to prospectively assess the effects of guideline compliance on outcomes and to formulate and refine new schemata to address emerging problems.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805630 | PMC |
| http://dx.doi.org/10.1016/j.ijregi.2023.12.002 | DOI Listing |
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