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Endogenous origin of infecting hospitalized patients in Ecuador. | LitMetric

Endogenous origin of infecting hospitalized patients in Ecuador.

Infect Prev Pract

Instituto de Microbiología, Universidad San Francisco de Quito USFQ, Quito, Ecuador.

Published: March 2024

Recent evidence suggests that , a bacterium that has the ability to cause deadly infections in hospitalized patients, could originate in the patient's own flora. We employed the Oxford Nanopore platform to obtain whole genome sequences (WGS) from clinical and rectal screen strains belonging to 15 patients from two hospitals. Our study found evidence that clinical and rectal isolates were clonal, with some evidence suggesting that the infecting strain was present in the patient's intestine at the time of admission, ruling out hospital acquisition. The use of WGS analysis is crucial to detect alternative sources of . to develop new preventive measures against these serious infections.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805645PMC
http://dx.doi.org/10.1016/j.infpip.2023.100331DOI Listing

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