AI Article Synopsis
- - The study aims to assess the impact of a single preoperative dose of gabapentin (15 mg/kg) on acute postoperative pain in children aged 8-14 undergoing urogenital surgeries under general anesthesia.
- - Sixty patients were divided into two groups, with one group receiving gabapentin mixed with honey and the other receiving only honey before surgery, measuring outcomes like fentanyl consumption and time to first pain relief.
- - Results showed that the gabapentin group used less fentanyl and experienced a longer time to first pain relief; however, it was also linked to increased sedation, highlighting the need to balance pain management with potential side effects.
Article Abstract
Background And Aims: Surgical procedure commonly performed in the advanced pediatric age group includes urogenital surgery, adenotonsillectomy, etc., Aim: The aim of this study is to determine the effect of single-dose gabapentin 15 mg/kg on acute pain in the immediate postoperative period in patients aged 8-14 years undergoing surgeries under general anesthesia.
Material And Methods: After the approval from the institutional ethical committee, 60 American Society of Anesthesiologists (ASA) I and II patients aged 8-14 years undergoing urogenital surgeries (orchidopexy/urethroplasty) under general anesthesia were included in this study. The patients were assigned into one of the two treatment groups. Patients in group I received oral gabapentin 15 mg/kg dissolved in 5 mL of honey 2 h before surgery, while patients in group II received 5 mL honey orally 2 h before surgery.
Results: A total of 60 patients participated. Patients in group I had lower consumption of fentanyl perioperatively (intraoperatively: 1.36 ± 0.70 mcg/kg; postoperatively: 2.36 ± 0.795 mcg/kg) than group II (intraoperatively: 1.8 ± 0.6 mcg/kg; postoperatively: 2.9 ± 0.47 mcg/kg). The differences in the two groups were significant. The time to first rescue analgesia was greater in group I (3.03 ± 0.60 h) than in group II (2.26 ± 0.57 h). There was an increase in sedation score in the treatment group.
Conclusion: Our clinical study demonstrates that a 15 mg/kg single preemptive oral dose of gabapentin might reduce the requirement of analgesics perioperatively in pediatric urogenital surgery but might also be associated with undesirable effects such as increased sedation.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10805194 | PMC |
| http://dx.doi.org/10.4103/joacp.joacp_503_21 | DOI Listing |
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