Introduction: Hamartoma is a tumor-like malformation that represents a focal proliferation of normal cells. Hamartoma of the soft palate is a rare entity, which can lead to serious, life-threatening clinical manifestations, given its anatomical location. However, if properly treated surgically, their prognosis is excellent.
Case Presentation: The literature reports very few similar cases. So, we report a case of hamartoma of the soft palate, which presented as a sessile velar outgrowth arising on the midline of a 12-day-old newborn. The final diagnosis was based on histopathology. The patient was treated surgically and had excellent evolution. Clinical Discussion. Clinical examination shows hamartomas of the palate to be polyploid lesions, with a firm surface. A CT scan and magnetic resonance imaging (MRI) are indicated to establish the extent of the tumor. The diagnosis of certainty is determined by a histopathological examination. The only treatment is surgery, generally via the transoral approach. Prognosis is excellent.
Conclusion: Hamartomas of the palate are diagnosed histologically, with imaging being of great help in assessing extension, and their therapeutic management is exclusively surgical. The prognosis after successful surgery is practically always good, with no recurrence.
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http://dx.doi.org/10.1016/j.ijscr.2024.109281 | DOI Listing |
Cureus
November 2024
Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Hepatic mesenchymal hamartoma (HMH) is an uncommon, benign liver tumor predominantly affecting children under three years of age. It is characterized histologically by disorganized mesenchymal stroma, abnormal bile ducts, blood vessels, and hepatocytes. HMH can present as a large cystic mass, a solid mass, or a combination of both.
View Article and Find Full Text PDFJ Pers Med
December 2024
Radiological Sciences Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, AOUP "Paolo Giaccone", Via del Vespro 129, 90127 Palermo, Italy.
Nasal and paranasal sinus masses can arise from a wide range of conditions, both benign and malignant, as well as congenital or acquired. Diagnosing these masses is often challenging, requiring a combination of nasal endoscopy, imaging studies, and histopathological analysis. Initial imaging frequently involves computed tomography or cone beam computed tomography (CBCT) to evaluate the bony anatomy of the nasal cavity and surrounding sinuses, while magnetic resonance imaging (MRI) is typically used for detailed assessment of soft tissues and to aid in differential diagnosis when the findings are inconclusive.
View Article and Find Full Text PDFJ Ultrasound Med
December 2024
Department of Dermatology, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Smooth muscle hamartoma (SMH) of the skin is a cutaneous benign proliferation of mature smooth muscle. Congenital SMH (CSMH) of the skin represents the most frequent type, and to date, there are no reports on its ultrasonographic pattern. A retrospective study of the color Doppler ultrasound (US) images of six CSMH patients at high and ultra-high frequencies was performed.
View Article and Find Full Text PDFJ Am Podiatr Med Assoc
November 2024
*Department of Orthopaedics and Traumatology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Zhonghua Jie He He Hu Xi Za Zhi
October 2024
Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Soochow University, Suzhou 215006, China.
Pulmonary hamartomas are the most common benign tumors of the lung, typically solitary with a diameter≤4 cm, and rarely undergo malignant transformation. We reported a case of multiple pulmonary hamartomas with malignant transformation of a giant pulmonary hamartoma (approximately 10 cm×12 cm in size). The patient was a 61-year-old female who sought medical attention for the discovery of multiple lesions in the right lung during a routine examination.
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