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Clinical Implication of Prone Position Electrocardiograms in Patients With COVID-19.
Clin Cardiol
January 2025
Second Department of Internal Medicine, University of Toyama, Toyama, Japan.
Background: Initial clinical studies of pulsed field ablation (PFA) to treat atrial fibrillation (AF) indicated a >90% durability rate of pulmonary vein isolation (PVI). However, these studies were largely conducted in single centers and involved a limited number of operators. The electrophysiological findings and outcomes in patients undergoing repeat ablation after an initial PF ablation for AF are incompletely understood.
View Article and Find Full Text PDFMismatch negativity in children with developmental Dyslexia.
Int J Pediatr Otorhinolaryngol
January 2025
Level IV, Department of Health and Human Communication, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:
Objective: To describe and compare the latencies and amplitudes of Mismatch Negativity between children with and without Developmental Dyslexia.
Methods: Cross-sectional and comparative study, consisting of a study group of 52 children with Developmental Dyslexia and a control group of 52 children with typical development, matched by age and sex, aged between 9 years and 11 years and 11 months of both sexes. All participants underwent Otoscopy, Acoustic Immittance Measurements, Pure Tone Audiometry, Speech Audiometry, Brainstem Auditory Evoked Potential and Mismatch Negativity.
Stimulating the regenerative capacity of the human retina with proneural transcription factors in 3D cultures.
Proc Natl Acad Sci U S A
January 2025
Department of Biological Structure, University of Washington, Seattle, WA 98125.
Retinal diseases often lead to degeneration of specific retinal cell types with currently limited therapeutic options to replace the lost neurons. Previous studies have reported that overexpression of or combinations of proneural factors in Müller glia (MG) induce regeneration of functional neurons in the adult mouse retina. Recently, we applied the same strategy in dissociated cultures of fetal human MG and although we stimulated neurogenesis from MG, our effect in 2D cultures was modest and our analysis of newborn neurons was limited.
View Article and Find Full Text PDFGene in Patients With Cardiomyopathy: Phenotypic Expression for Loss-of-Function Versus Hotspot Variants.
Circ Heart Fail
January 2025
Assistance Publique Hopitaux de Paris (APHP), Pitié-Salpêtrière Hospital, Institute of Cardiology and Institute for Cardiometabolism and Nutrition, Paris, France (A.H., M.L., P. Charron, E.G.).
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