Antioxidant effects of rosemary oil in streptozotocin-induced diabetic rats.

This study designed to investigate the potential effects of rosemary oil on oxidative stress markers in streptozotocin-induced diabetic rats. The rats divided into four groups such as control group, rosemary group, diabetes group and diabetes + rosemary group. Blood samples were analyzed to assess with enzyme-linked immunosorbent assay various parameters including malondialdehyde (MDA), glutathione (GSH), super oxide dismutase (SOD). Insulin and glucose levels were also determined through autoanalyzer. The results indicated significant increase in MDA levels and significant decrease in GSH and SOD levels in the diabetes group. Following the administration of rosemary oil to streptozotocin-induced diabetic rats, a significant decrease in MDA level and significant increase in GSH and SOD levels was observed in comparison to the diabetes group. In the research, rats induced with streptozotocin-induced diabetes were displayed notably lower insulin levels compared to the control group, accompanied by significantly higher glucose levels. Upon the administration of rosemary oil to these diabetic rats, there was marked amelioration in insulin and glucose levels compared to the untreated diabetic group. These findings collectively suggest that the utilization of rosemary oil in diabetic rats potentially have positive effects on oxidative stress markers, indicating its promising role as a therapeutic intervention in diabetic conditions.