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http://dx.doi.org/10.4103/jips.jips_545_23 | DOI Listing |
Syst Rev
January 2025
Centre for Clinical Intervention Research, Copenhagen Trial Unit, Capital Region of Denmark, Copenhagen, Denmark.
Background: Type 1 diabetes is a serious, chronic disorder with an increasing incidence among children and adolescents. Glycemic control in individuals with type 1 diabetes is better managed through a basal-bolus regimen with either regular human or rapid-acting insulin analogues administered as a bolus at mealtimes. Rapid-acting insulin analogues have been hypothesized to cause optimal glycemic control and less risk of hypoglycemic episodes compared to regular human insulins.
View Article and Find Full Text PDFTrials
January 2025
Department of Neurology, the First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Background: Early neurological deterioration (END) is a critical determinant influencing the short-term prognosis of acute ischemic stroke (AIS) patients and is associated with increased mortality rates among hospitalized individuals. AIS frequently coexists with coronary heart disease (CHD), complicating treatment and leading to more severe symptoms and worse outcomes. Shared risk factors between CHD and AIS, especially elevated low-density lipoprotein cholesterol (LDL-C), contribute to atherosclerosis and inflammation, which worsen brain tissue damage.
View Article and Find Full Text PDFNutr Metab (Lond)
January 2025
Department of Sports Medicine, China Medical University, Taichung City, Taiwan.
Background: Intermittent fasting (IF) can be an effective dietary therapy for weight loss and improving cardiometabolic health. However, there is scant evidence regarding the role of IF on indicators of liver function, particularly in adults with metabolic disorders. Therefore, we performed a systematic review and meta-analysis to investigate the effects of IF on liver function in adults with metabolic disorders.
View Article and Find Full Text PDFTrials
January 2025
Department of Physiotherapy, Melbourne School of Health Science, University of Melbourne, Melbourne, Australia.
Background: Non-invasive ventilation (NIV) uses positive pressure to assist people with respiratory muscle weakness or severe respiratory compromise to breathe. Most people use this treatment during sleep when breathing is most susceptible to instability. The benefits of using NIV in motor neurone disease (MND) are well-established.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Epidemiology, School of Health, Mashhad University of Medical Science, Mashhad, Iran.
Background: In order to increase the stability of tibial component in total knee arthroplasty (TKA), intramedullary stem extensions (SE) have been developed. The aim of this systematic review and meta-analysis is to address the critical knowledge gap on post-operative outcomes and complications rate comparison between tibial component with SE compared to the tibial component standard configuration (SC) in primary cemented TKA.
Methods: We conducted a comprehensive search of online databases, including Pubmed, Embase, ISI Web of science, Cochrane Library, and Scopus, using the following MeSH terms, (total knee arthroplasty) OR (TKA) OR (total knee replacement) AND (Tibial stem) OR (stem extension) OR (long stem).
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