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Superstable lipid vacuoles endow cartilage with its shape and biomechanics.
Science
January 2025
Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA.
Conventionally, the size, shape, and biomechanics of cartilages are determined by their voluminous extracellular matrix. By contrast, we found that multiple murine cartilages consist of lipid-filled cells called lipochondrocytes. Despite resembling adipocytes, lipochondrocytes were molecularly distinct and produced lipids exclusively through de novo lipogenesis.
View Article and Find Full Text PDF"They Surge-on…The Journey of an Early Career Plastic Surgeon in India as I see it".
Indian J Plast Surg
December 2024
Endocrinology, Yenepoya Medical College Hospital, Mangaluru, Karnataka, India.
The journey to becoming a plastic surgeon is a long one. Most nonsurgeons are unaware of the actual scope of plastic surgery and the spectrum of surgeries done by plastic surgeons. The constant look-out for "cutting chances" from early in the career can be quite exhausting and may take a toll on the professional relationships as well as personal lives of plastic surgeons.
View Article and Find Full Text PDFA temporary hospital intensive care unit: a preparedness concept to increase intensive care capacity.
Scand J Trauma Resusc Emerg Med
December 2024
Department of Research and Development, Haukeland University Hospital, Bergen, Norway.
Introduction: Norway faced the possibility of the most significant strain on its intensive care capacity in decades during the COVID-19 pandemic. All Regional Health Authorities in Norway were instructed to prepare for an increase in Intensive Care Units (ICU) capacity demands. To address the surge in demand for critical care, a gymnasium within Haukeland University Hospital premises was planned to be used as a 20-bed temporary ICU.
View Article and Find Full Text PDFMulti-disciplinary mass burn casualty simulation exercise.
Burns
December 2024
Adult Burns Service, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Disaster simulation exercises are important to test service processes, capabilities, and deficiencies; disaster response planning should encompass the entire multidisciplinary team over an extended period. Our service simulated a modest eight burn casualty scenario to test our service capabilities over a 10-week period across medical, nursing, and allied health professions. Requirements due to the mass burns casualty cohort were predicted in terms of theatre requirements, allied health treatment hours required, and nursing hours requirements.
View Article and Find Full Text PDFEnhancing trauma care in Ukraine amid conflict: A successful implementation of the modified advanced trauma life support course in an active war zone.
World J Surg
November 2024
Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Background: Following the 2022 Russian invasion, Ukraine's healthcare system suffered extensive damage, with over 1000 medical facilities destroyed, exacerbating the trauma care crisis. The absence of standardized trauma training left Ukrainian healthcare providers ill-equipped to manage the surge in trauma cases amid conflict. To bridge this gap, we implemented advanced trauma life support (ATLS) courses in Ukraine amid active warfare, aiming to enhance trauma care expertise among healthcare professionals.
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